Dr Eva Perez

Real name:

Postdoctoral Scientist

Immunology, Vaccinology, Virology

Eva studied for her DVM at the University of Barcelona, Spain. After completing her PhD in Medicine and Animal Health at the Centre of Research in Animal Health (CReSA), Barcelona, she took up a post-doctoral position at Plum Island Animal Disease Center (PIADC), USA. During this time, Eva worked on the innate immune response and the use of biotherapeutics for controlling foot-and-mouth disease (FMD). Eva then moved to a second postdoc at The Pirbright Institute, in the UK, where she is currently investigating the development of new vaccines against FMD and the persistence of FMD virus in mice models and in its natural host, the African buffalo.

News
Publications

New insights into how foot-and-mouth disease virus interacts with the immune system discovered at Pirbright

New research giving insight into the persistence of highly contagious foot-and-mouth disease virus features on front cover of Science Magazine

Pirbright scientists shed new light on foot-and-mouth disease virus evolution

Pirbright grants licence for new foot-and-mouth disease vaccine

Persistently infected African buffalo not a likely cause of new FMD outbreaks say Pirbright scientists

Perez-Martin E, Beechler B, Zhang F, Scott K, de Klerk-Lorist L-M, Limon G, Dugovich B, Gubbins S, Botha A, Hetem R, van Schalkwyk L, Juleff N, Maree F F, Jolles A, Charleston B (2022)

Viral dynamics and immune responses to foot-and-mouth disease virus in African buffalo (Syncerus caffer)

Veterinary Research 53 (1) , 63

Publisher’s version: https://doi.org/10.1186/s13567-022-01076-3

Gordon L, Mabbott N, Wells J, Kulik L, Juleff N, Charleston B, Perez-Martin E (2022)

Foot-and-mouth disease virus localisation on follicular dendritic cells and sustained induction of neutralising antibodies is dependent on binding to complement receptors (CR2/CR1)

PLoS Pathogens 18 (5) , e1009942

Publisher’s version: https://doi.org/10.1371/journal.ppat.1009942

Jolles A, Gorsich E, Gubbins S, Beechler B, Buss P, Juleff N, de Klerk-Lorist L-M, Maree F, Perez-Martin E, van Schalkwyk O L, Scott K, Zhang F, Medlock J, Charleston B (2021)

Endemic persistence of a highly contagious pathogen: foot-and-mouth disease in its wildlife host

Science 374 (6563) , 104-109

Publisher’s version: https://doi.org/10.1126/science.abd2475

Jackson B, Harvey Y, Perez-Martin E, Wilsden G, Juleff N, Charleston B, Seago J (2021)

The selection of naturally stable candidate foot-and-mouth disease virus vaccine strains for East Africa

Vaccine 39 (35) , 5015-5024

Publisher’s version: https://doi.org/10.1016/j.vaccine.2021.07.001

Ferretti L, Pérez-Martín E, Zhang F, Maree F, de Klerk-Lorist L-M, van Schalkwykc L, Juleff N D, Charleston B, Ribeca P (2020)

Pervasive within-host recombination and epistasis as major determinants of the molecular evolution of the foot-and-mouth disease virus capsid

PLoS Pathogens 16 (1) , e1008235

Publisher’s version: https://doi.org/10.1371/journal.ppat.1008235

Cortey M, Ferretti L, Perez-Martin E, Zhang F, de Klerk-Lorist L M, Scott K, Freimanis G, Seago J, Ribeca P, van Schalkwyk L, Juleff N D, Maree F F, Charleston B (2019)

Persistent infection of African buffalo (Syncerus caffer) with foot-and-mouth disease virus: limited viral evolution and no evidence of antibody neutralization escape

Journal of Virology 93 (15) , e00563-19

Publisher’s version: https://doi.org/10.1128/JVI.00563-19

Groups

Viral Immunology

Dr Eva Perez

New insights into how foot-and-mouth disease virus interacts with the immune system discovered at Pirbright

New research giving insight into the persistence of highly contagious foot-and-mouth disease virus features on front cover of Science Magazine

Pirbright scientists shed new light on foot-and-mouth disease virus evolution

Pirbright grants licence for new foot-and-mouth disease vaccine

Persistently infected African buffalo not a likely cause of new FMD outbreaks say Pirbright scientists

Viral dynamics and immune responses to foot-and-mouth disease virus in African buffalo (Syncerus caffer)

Foot-and-mouth disease virus localisation on follicular dendritic cells and sustained induction of neutralising antibodies is dependent on binding to complement receptors (CR2/CR1)

Endemic persistence of a highly contagious pathogen: foot-and-mouth disease in its wildlife host

The selection of naturally stable candidate foot-and-mouth disease virus vaccine strains for East Africa

Pervasive within-host recombination and epistasis as major determinants of the molecular evolution of the foot-and-mouth disease virus capsid

Persistent infection of African buffalo (Syncerus caffer) with foot-and-mouth disease virus: limited viral evolution and no evidence of antibody neutralization escape

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