Dr Katy Moffat

Real name:

Postdoctoral Scientist

Bioimaging, Cell Biology, Immunology

Katy Moffat studied for her BSc Hons in Biochemistry at Stirling University and then completed her PhD at the John Innes centre, studying the effects of gene silencing on virus infection in plants. She joined the Immunology group at The Pirbright Institute in 2001 to examine interactions between foot-and-mouth disease virus (FMDV) and intracellular proteins during virus replication.

Katy discovered that FMDV infection lead to a disruption of the cellular protein secretory pathway and the viral protein responsible differed to that of another picornavirus, Poliovirus. In 2006, Katy became part of the Vaccinology group and is currently studying responses of dendritic cells (immune cells) to bluetongue virus (BTV) infection.

News
Publications

Berryman S, Moffat K, Harak C, Lohmann V, Jackson T (2016)

Foot-and-mouth disease virus replicates independently of phosphatidylinositol 4-phosphate and type III phosphatidylinositol-4-kinases

Journal of General Virology 97 (8) , 1841-1852

Publisher’s version: http://dx.doi.org/10.1099/jgv.0.000485

Darpel K E, Barber J, Hope A, Wilson A J, Gubbins S, Henstock M, Frost L, Batten C, Veronesi E, Moffat K, Carpenter S, Oura C, Mellor P S, Mertens P P C (2016)

Using shared needles for subcutaneous inoculation can transmit bluetongue virus mechanically between ruminant hosts

Scientific Reports 6 , 20627

Publisher’s version: http://dx.doi.org/10.1038/srep20627

Groups

Bioimaging

Dr Katy Moffat

Pirbright scientists use ‘molecular magnets’ to discover FMD virus segments that could improve vaccine effectiveness

Pirbright generates first pig flu antibodies that could improve human treatments and guide flu vaccine selection

Early animal studies by Pirbright and Oxford yield promising results for new potential COVID-19 vaccine

Pirbright study shows how SARS-CoV-2 could have adapted from bats to humans and which other animals it could infect

Studies at Pirbright demonstrate two doses of Oxford University’s COVID-19 vaccine boosts immune response in pigs

A simple and rapid approach to develop recombinant avian herpesvirus vectored vaccines using CRISPR/Cas9 system

Foot-and-mouth disease virus replicates independently of phosphatidylinositol 4-phosphate and type III phosphatidylinositol-4-kinases

Using shared needles for subcutaneous inoculation can transmit bluetongue virus mechanically between ruminant hosts

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Dr Katy Moffat

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