Prof Bryan Charleston

Real name:

Director

Immunology, Veterinary Practitioner, Virology

Prof Bryan Charleston obtained a BVetMed from the Royal Veterinary College, University of London, UK in 1982. After a period of time in Large Animal Practice, he studied for a Masters degree in Molecular Biology at University College London in 1988, then a PhD degree, as a Wellcome Trust Scholar, from the University of London, UK, in 1991. He then carried out postdoctoral research, as a Wellcome Trust Post-doctoral fellow, at the Royal Veterinary College and the Babraham Institute, Cambridge for three years.

He joined The Pirbright Institute in 1994 and focused on studies of the immune response to viral infections in cattle. In addition, he provided advice and expertise on the design of infectious disease challenge models for a wide range of pathogens in important agricultural species. His research is focused on understanding the immune response to foot-and–mouth disease virus (FMDV) in cattle to develop novel vaccines.

News
Publications

Shirley M W, Charleston B, King D P (2011)

New opportunities to control livestock diseases in the post-genomics era

Journal of Agricultural Science 149 , 115-121

Publisher’s version: http://dx.doi.org/10.1017/s0021859610001103

Windsor M A, Carr B V, Bankowski B, Gibson D, Reid E, Hamblin P, Gubbins S, Juleff N, Charleston B (2011)

Cattle remain immunocompetent during the acute phase of foot-and-mouth disease virus infection

Veterinary Research 42 , 108

Publisher’s version: http://dx.doi.org/10.1186/1297-9716-42-108

McLaughlin K, Carr V B, Iqbal M, Seago J, Lefevre E A, Robinson L, Prentice H, Charleston B (2011)

Hsp110-mediated enhancement of CD4+ T cell responses to the envelope glycoprotein of members of the family Flaviviridae in vitro does not occur in vivo

Clinical and Vaccine Immunology 18 (2) , 311-317

Publisher’s version: http://dx.doi.org/10.1128/CVI.00414-10

Reid E, Juleff N, Gubbins S, Prentice H, Seago J, Charleston B (2011)

Bovine plasmacytoid dendritic cells are the major source of type I interferon in response to foot-and-mouth disease virus in vitro and in vivo

Journal of Virology 85 (9) , 4297-4308

Publisher’s version: http://dx.doi.org/10.1128/JVI.02495-10

Robinson L, Windsor M, McLaughlin K, Hope J, Jackson T, Charleston B (2011)

Foot-and-mouth disease virus exhibits an altered tropism in the presence of specific immunoglobulins, enabling productive infection and killing of dendritic cells

Journal of Virology 85 (5) , 2212-2223

Publisher’s version: http://dx.doi.org/10.1128/JVI.02180-10

Groups

Viral Immunology

Prof Bryan Charleston

Pirbright to join efforts in monkeypox research as part of new consortium

COVID-19 booster vaccinations help the immune system fight SARS-CoV-2

New insights into how foot-and-mouth disease virus interacts with the immune system discovered at Pirbright

New Chair of the Pirbright Trustee Board

Pirbright continues to grow international collaborations to fight and prevent infectious disease

The classical swine fever virus N-terminal protease N(pro) binds to cellular HAX-1

New opportunities to control livestock diseases in the post-genomics era

Cattle remain immunocompetent during the acute phase of foot-and-mouth disease virus infection

Hsp110-mediated enhancement of CD4+ T cell responses to the envelope glycoprotein of members of the family Flaviviridae in vitro does not occur in vivo

Bovine plasmacytoid dendritic cells are the major source of type I interferon in response to foot-and-mouth disease virus in vitro and in vivo

Foot-and-mouth disease virus exhibits an altered tropism in the presence of specific immunoglobulins, enabling productive infection and killing of dendritic cells

Pages

Contact

Trim content

You are here

Groups

Prof Bryan Charleston

Pages

Contact

Trim content