Prof Bryan Charleston

Director

Immunology, Veterinary Practitioner, Virology

Prof Bryan Charleston obtained a BVetMed from the Royal Veterinary College, University of London, UK in 1982. After a period of time in Large Animal Practice, he studied for a Masters degree in Molecular Biology at University College London in 1988, then a PhD degree, as a Wellcome Trust Scholar, from the University of London, UK, in 1991. He then carried out postdoctoral research, as a Wellcome Trust Post-doctoral fellow, at the Royal Veterinary College and the Babraham Institute, Cambridge for three years.

He joined The Pirbright Institute in 1994 and focused on studies of the immune response to viral infections in cattle. In addition, he provided advice and expertise on the design of infectious disease challenge models for a wide range of pathogens in important agricultural species. His research is focused on understanding the immune response to foot-and–mouth disease virus (FMDV) in cattle to develop novel vaccines.

News
Publications

Charleston B, Bankowski B M, Gubbins S, Chase-Topping M E, Schley D, Howey R, Barnett P V, Gibson D, Juleff N D, Woolhouse M E J (2011)

Relationship between clinical signs and transmission of an infectious disease and the implications for control

Science 332 (6030) , 726-729

Publisher’s version: http://dx.doi.org/10.1126/science.1199884

Charleston B, Rodriguez L L (2011)

Understanding foot-and-mouth disease virus early pathogenesis and immune responses

Transboundary and Emerging Diseases 58 (4) , 281-282

Publisher’s version: http://dx.doi.org/10.1111/j.1865-1682.2011.01237.x

Cubillos-Zapata C, Guzman E, Turner A, Gilbert S C, Prentice H, Hope J C, Charleston B (2011)

Differential effects of viral vectors on migratory afferent lymph dendritic cells in vitro predict enhanced immunogenicity in vivo

Journal of Virology 85 (18) , 9385-9394

Publisher’s version: http://dx.doi.org/10.1128/JVI.05127-11

Golde W T, de Los Santos T, Robinson L, Grubman M J, Sevilla N, Summerfield A, Charleston B (2011)

Evidence of activation and suppression during the early immune response to foot-and-mouth disease virus

Transboundary and Emerging Diseases 58 (4) , 283-290

Publisher’s version: http://dx.doi.org/10.1111/j.1865-1682.2011.01223.x

McLaughlin K, Carr V B, Iqbal M, Seago J, Lefevre E A, Robinson L, Prentice H, Charleston B (2011)

Hsp110-mediated enhancement of CD4+ T cell responses to the envelope glycoprotein of members of the family Flaviviridae in vitro does not occur in vivo

Clinical and Vaccine Immunology 18 (2) , 311-317

Publisher’s version: http://dx.doi.org/10.1128/CVI.00414-10

Groups

Viral Immunology

Prof Bryan Charleston

Pirbright enters bioimaging collaboration with Diamond Light Source

One Health Day: Pirbright research to protect animals and humans

Pirbright collaboration proves Rift Valley fever vaccine safe in pregnant animals

Pirbright grants licence for new foot-and-mouth disease vaccine

Pirbright Science Advisory Board member receives International Award

Characterization of epitope-tagged foot-and-mouth disease virus

Relationship between clinical signs and transmission of an infectious disease and the implications for control

Understanding foot-and-mouth disease virus early pathogenesis and immune responses

Differential effects of viral vectors on migratory afferent lymph dendritic cells in vitro predict enhanced immunogenicity in vivo

Evidence of activation and suppression during the early immune response to foot-and-mouth disease virus

Hsp110-mediated enhancement of CD4+ T cell responses to the envelope glycoprotein of members of the family Flaviviridae in vitro does not occur in vivo

Pages

Contact

Trim content

You are here

Groups

Prof Bryan Charleston

Pages

Contact

Trim content