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Cross-protectivity of henipavirus soluble glycoprotein in an in vivo model of Nipah virus disease

Introduction: Nipah virus (NiV) is one of a group of highly pathogenic viruses classified within the Henipavirus genus. Since 2012 at least 11 new henipa-like viruses have been identified, including from new locations and reservoir hosts; the pathogenicity of these new…

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The efficacy of vector-proof accommodation for the protection of livestock against Culicoides biting midges

Background Bluetongue virus serotype 3 emerged in northern Europe and the UK for the first time in 2023, causing significant losses of domestic ruminants. Vector-proof accommodation is considered a potential control measure to reduce host-vector contact, but this has not…

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The efficacy of vector-proof accommodation for the protection of livestock against Culicoides biting midges

Background Bluetongue virus serotype 3 emerged in northern Europe and the UK for the first time in 2023, causing significant losses of domestic ruminants. Vector-proof accommodation is considered a potential control measure to reduce host-vector contact, but this has not…

Large herd of white cattle in Ghana stood in a line in front of a watering hole. At the other side of the watering hole are more cattle in the water.

African partnership advances animal health research

Researchers from The Pirbright Institute are helping to strengthen ties in animal research and data science between Ghana and the UK. The partnership, led by the Roslin Institute and the University of Ghana, aims to develop Ghanaian local expertise in animal health and long…

Researcher in a white lab coat, light blue gloves with a hair net and face mask stood in front of a trolley with plastic tubes on. The researcher is placing a small plastic box into a cabinet that is branded with Quantoom Biosciences Ntensify

CVIM partners Quantoom Biosciences to advance vaccine development

The Centre for Veterinary Vaccine Innovation and Manufacturing (CVIM) has teamed up with Quantoom Biosciences to advance mRNA and saRNA vaccine development. Based at The Pirbright Institute, CVIM is actively engaged in mRNA and saRNA vaccine research as part of its mission…

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Population Structure of the Invasive Asian Tiger Mosquito, Aedes albopictus, in Europe

The Asian tiger mosquito, Aedes albopictus, is currently the most widespread invasive mosquito species in the world. It poses a significant threat to human health, as it is a vector for several arboviruses. We used a SNP chip to genotype 748 Ae. albopictus mosquitoes from 41…

Prof Bryan Charleston and Dr Linda Dixon who is holding a box of flowers stood in front of a screen with agenda of symposium

Symposium celebrates scientist’s 40-year career

International scientists, colleagues and friends have celebrated the 40-year career of Dr Linda Dixon at a special symposium at The Pirbright Institute. Dr Dixon, who recently retired from leading the African Swine Fever Virus (ASFV) group, is amongst the most highly cited…

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Mapping novel antigenic determinants on foot-and-mouth disease virus serotype Asia 1 using neutralising monoclonal antibody resistant mutants

Foot-and-mouth disease (FMD) is a severe and, highly contagious viral disease caused by FMD virus (FMDV) that primarily targets ungulates. Identifying neutralising antigenic sites on the virus is crucial for understanding the virus's antigenic characteristics. Numerous…

Eight mpox cells under the microscope and coloured bright blue

Mpox

Mpox is a contagious viral disease affecting humans, with global health implications.

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Recombinant infectious bronchitis virus containing mutations in non-structural proteins 10, 14, 15, and 16 and within the macrodomain provides complete protection against homologous challenge

Infectious bronchitis virus (IBV) is the etiological agent of infectious bronchitis, an acute highly contagious economically important disease of chickens. Vaccination uses live attenuated vaccines (LAVs) that are generated via serial passage of a virulent field isolate…