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Impact of Eimeria tenella coinfection on Campylobacter jejuni colonization of the chicken

Eimeria tenella can cause the disease coccidiosis in chickens. The direct and often detrimental impact of this parasite on chicken health, welfare, and productivity is well recognized; however, less is known about the secondary effects that infection may have on other gut…

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Engineered action at a distance: blood-meal-inducible paralysis in Aedes aegypti

BACKGROUND: Population suppression through mass-release of Aedes aegypti males carrying dominant-lethal transgenes has been demonstrated in the field. Where population dynamics show negative density-dependence, suppression can be enhanced if lethality occurs after the…

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A deep-sequencing workflow for the fast and efficient generation of high-quality African swine fever virus whole-genome sequences

African swine fever (ASF) is a severe disease of suids caused by African swine fever virus (ASFV). Its dsDNA genome (170-194 kbp) is scattered with homopolymers and repeats as well as inverted-terminal-repeats (ITR), which hamper whole-genome sequencing. To date, only a few…

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A deep-sequencing workflow for the fast and efficient generation of high-quality African swine fever virus whole-genome sequences

African swine fever (ASF) is a severe disease of suids caused by African swine fever virus (ASFV). Its dsDNA genome (170-194 kbp) is scattered with homopolymers and repeats as well as inverted-terminal-repeats (ITR), which hamper whole-genome sequencing. To date, only a few…

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Improved PCR diagnostics using up-to-date in silico validation: an F-gene RT-qPCR assay for the detection of all four lineages of peste des petits ruminants virus

Peste des petits ruminants (PPR) is a globally significant disease of small ruminants caused by the peste des petits ruminants virus (PPRV) that is considered for eradication by 2030 by the United Nations Food and Agriculture Organisation (FAO). Critical to the eradication…

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Combatting the looming threat of bluetongue

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Crystal structure of African swine fever virus A179L with the autophagy regulator Beclin

Subversion of programmed cell death-based host defence systems is a prominent feature of infections by large DNA viruses. African swine fever virus (ASFV) is a large DNA virus and sole member of the Asfarviridae family that harbours the B-cell lymphoma 2 or Bcl-2 homolog…

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Crystal structure of African swine fever virus A179L with the autophagy regulator Beclin

Subversion of programmed cell death-based host defence systems is a prominent feature of infections by large DNA viruses. African swine fever virus (ASFV) is a large DNA virus and sole member of the Asfarviridae family that harbours the B-cell lymphoma 2 or Bcl-2 homolog…

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Bead-based multiplex assay for the simultaneous detection of antibodies to African swine fever virus and classical swine fever virus

African swine fever (ASF) and Classical swine fever (CSF) are both highly contagious diseases of domestic pigs and wild boar. In the last years, several cases of both diseases have been reported in the Caucasus, Russian Federation and Eastern Europe. Thus, the probability of…

Pirbright launches The Immunological Toolbox website

Scientists from The Pirbright Institute and The Roslin Institute have launched The Immunological Toolbox, a website that provides a platform for veterinary researchers to find resources and collaborate. The Toolbox aims to remove barriers to veterinary vaccine development by…