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Viral emergence in marine mammals in the North Pacific may be linked to Arctic sea ice reduction

Climate change-driven alterations in Arctic environments can influence habitat availability, species distributions and interactions, and the breeding, foraging, and health of marine mammals. Phocine distemper virus (PDV), which has caused extensive mortality in Atlantic…

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Viral emergence in marine mammals in the North Pacific may be linked to Arctic sea ice reduction

Climate change-driven alterations in Arctic environments can influence habitat availability, species distributions and interactions, and the breeding, foraging, and health of marine mammals. Phocine distemper virus (PDV), which has caused extensive mortality in Atlantic…

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Immunogenicity and protective efficacy of seasonal human live attenuated cold-adapted influenza virus vaccine in pigs

Influenza A virus infection is a global health threat to livestock and humans, causing substantial mortality and morbidity. As both pigs and humans are readily infected with influenza viruses of similar subtype, the pig is a robust and appropriate model for investigating…

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The porcine deltacoronavirus replication organelle comprises double-membrane vesicles and zippered endoplasmic reticulum with double-membrane spherules

Porcine deltacoronavirus (PDCoV) was first identified in Hong Kong in 2012 from samples taken from pigs in 2009. PDCoV was subsequently identified in the USA in 2014 in pigs with a history of severe diarrhea. The virus has now been detected in pigs in several countries…

Portrait of Holly Shelton

Science Spotlight: Dr Holly Shelton

Dr Holly Shelton joined The Pirbright Institute in 2011 and progressed to Group Leader in 2016. Dr Shelton leads the Influenza Viruses group which is working to understand how genetic changes in avian influenza viruses can alter disease severity, ease of transmission and the…

Camels in the RVF trials in Kenya

One Health Day: Pirbright research to protect animals and humans

One Health Day, celebrated on 3 November each year, raises awareness around the need for research to join across many disciplines to solve the world’s critical health challenges. The One Health agenda advocates that scientists consider how animal, human and plant health are…

Camels in the RVF trials in Kenya

One Health Day: Pirbright research to protect animals and humans

One Health Day, celebrated on 3 November each year, raises awareness around the need for research to join across many disciplines to solve the world’s critical health challenges. The One Health agenda advocates that scientists consider how animal, human and plant health are…

Camels in the RVF trials in Kenya

One Health Day: Pirbright research to protect animals and humans

One Health Day, celebrated on 3 November each year, raises awareness around the need for research to join across many disciplines to solve the world’s critical health challenges. The One Health agenda advocates that scientists consider how animal, human and plant health are…

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ICTV virus taxonomy profile: Caliciviridae

The family Caliciviridae includes viruses with single-stranded, positive-sense RNA genomes of 7.4-8.3 kb. The most clinically important representatives are human noroviruses, which are a leading cause of acute gastroenteritis in humans. Virions are non-enveloped with…

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Safety and efficacy of ChAdOx1 RVF vaccine against Rift Valley fever in pregnant sheep and goats

Rift Valley fever virus (RVFV) is a zoonotic mosquito-borne virus that was first discovered in Kenya in 1930 and has since spread to become endemic in much of Africa and the Arabian Peninsula. Rift Valley fever (RVF) causes recurrent outbreaks of febrile illness associated…