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A Chef and a person stood on grass together looking at the camera. Behind them on the left is a green cylinder with metal legs. White words on the green composter read "ridan food waste composter. keeping the world turning."

Mulch ado about food waste

A new composter is helping The Pirbright Institute recycle its food waste, fertilise allotments and reduce its carbon footprint. The hot aerobic composter uses no power and blends wood pellets with canteen waste to produce up to 6.5 tonnes of mulch a year on site. For every…

Small herd of white cattle in South Africa on dried grass. The image has a sunset haze to it.

Pirbright expertise informs economic analysis for foot-and-mouth disease control

How much should policymakers invest in controlling animal diseases that spread across national borders, who should pay, and will intervention really work? A researcher at The Pirbright Institute is one of a team of seven authors who have drafted a new handbook for the Food…

Small young yellow chick on sawdust. Both legs have little loose yellow rings

Pirbright’s openness on animal research rewarded

The Pirbright Institute’s commitment to openness on animal research has been rewarded with continued recognition from Understanding Animal Research (UAR). The three-year reaccreditation of the Institute as a Leader in Openness to 2028 marks the third renewal of the award for…

This scanning electron microscope image shows SARS-CoV-2 (yellow)—also known as 2019-nCoV, the virus that causes COVID-19—isolated from a patient in the U.S., emerging from the surface of cells (pink) cultured in the lab.

Pirbright in £10m collaboration to fight animal and plant disease

The Pirbright Institute has joined a £10m advanced technology surveillance programme to strengthen the UK’s biosecurity and protect animals, plants, people and trade. Advanced genome sequencing technologies - a method that reads the complete genetic code of a living organism…

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Multi-omics analysis reveals key immunogenic signatures induced by oncolytic Zika virus infection of paediatric brain tumour cells

Brain tumours disproportionately affect children and are the largest cause of paediatric cancer-related death. Novel therapies that engage the immune system, such as oncolytic viruses (OVs), hold great promise and are desperately needed. Zika virus (ZIKV) infects and…

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Direct amplification and sequencing of enterovirus genomes from clinical and wastewater samples reveals uncommon virus types in Cameroon

Knowledge about the genetic diversity of enteroviruses in sub-Saharan Africa remains biased by the fact that it has mainly been described through the characterization of specimens isolated in cell cultures. The aim of this study was to characterize enteroviruses that…

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Foot-and-Mouth Disease Vaccines by Design; Production of Capsid-Modified Foot-and-Mouth Disease Viruses with Improved Cell Culture Growth

Background/objectives: Vaccination is important for controlling foot-and-mouth disease (FMD) in endemic regions and to lessen the effects of outbreaks in FMD-free countries. The adaptation of FMD virus to BHK cells is a necessary but time-consuming and costly step in vaccine…

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Porcine respiratory coronavirus as a model for acute respiratory disease: mechanisms of different infection outcomes

Porcine respiratory coronavirus (PRCV) is a naturally occurring pneumotropic coronavirus in the pig, providing a valuable large animal model to study acute respiratory disease. PRCV pathogenesis and the resulting immune response were investigated in pigs, the natural large…

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SARS-CoV-2 variants retain high airborne transmissibility by different strategies

SARS-CoV-2 variants evolve to balance immune evasion and airborne transmission, yet the mechanisms remain unclear. In hamsters, first-wave, Alpha, and Delta variants transmitted efficiently via aerosols. Alpha emitted fewer viral particles than first-wave virus but…

Close up of two pink pigs lying on straw

Pigs provide insights into coronavirus-induced lung damage

Respiratory viruses are a major threat to global health, but why some people experience severe lung damage from infections like SARS-CoV-2 while others have mild symptoms is something that researchers have sought to understand. A new study lead by Pirbright researchers uses…