Two new genes have been identified in infectious bronchitis virus (IBV), a coronavirus that causes an acute, highly contagious and economically important respiratory disease of poultry. The research, carried out by scientists at The Pirbright Institute, raises the prospect that coronavirus genomes are more complex than previously thought. Understanding more about their basic biology can help to inform future vaccines and therapeutics.
Pirbright shows bird flu mutations could increase threat to poultry, but reduce potential to infect humans
Mutations in the H7N9 bird flu virus increase its replication rate and stability in avian cells, but reduce its preference for infecting human cells, a study from The Pirbright Institute has found. The results show that outbreaks in birds caused by strains with these mutations could pose a lower risk to human health, while remaining a significant threat to the poultry industry.