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Research paper

Role of African swine fever virus (ASFV) proteins EP153R and EP402R in reducing viral persistence in blood and virulence in pigs infected with BeninΔDP148R

The limited knowledge on the role of many of the approximately 170 proteins encoded by African swine fever virus restricts progress toward vaccine development. Previously, the DP148R gene was deleted from the genome of genotype I virulent Benin 97/1 isolate. This virus…
Read more
default publication image
Research paper

Role of African swine fever virus (ASFV) proteins EP153R and EP402R in reducing viral persistence in blood and virulence in pigs infected with BeninΔDP148R

The limited knowledge on the role of many of the approximately 170 proteins encoded by African swine fever virus restricts progress toward vaccine development. Previously, the DP148R gene was deleted from the genome of genotype I virulent Benin 97/1 isolate. This virus…
Read more
default publication image
Research paper

Endemic persistence of a highly contagious pathogen: foot-and-mouth disease in its wildlife host

Extremely contagious pathogens are a global biosecurity threat because of their high burden of morbidity and mortality, as well as their capacity for fast-moving epidemics that are difficult to quell. Understanding the mechanisms enabling persistence of highly transmissible…
Read more
default publication image
Research paper

Endemic persistence of a highly contagious pathogen: foot-and-mouth disease in its wildlife host

Extremely contagious pathogens are a global biosecurity threat because of their high burden of morbidity and mortality, as well as their capacity for fast-moving epidemics that are difficult to quell. Understanding the mechanisms enabling persistence of highly transmissible…
Read more
default publication image
Research paper

Immune response in mice immunized with chimeric H1 antigens

Identification of a universal influenza vaccine candidate has remained a global challenge for both humans and animals. This study describes an approach that uses consensus sequence building to generate chimeric HAs (cHAs): two resultant H1 HA-based chimeras comprising of…
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Research paper

Innate immune antagonism of mosquito-borne flaviviruses in humans and mosquitoes

Mosquito-borne viruses of the Flavivirus genus ( Flaviviridae family) pose an ongoing threat to global public health. For example, dengue, Japanese encephalitis, West Nile, yellow fever, and Zika viruses are transmitted by infected mosquitoes and cause severe and fatal…
Read more
default publication image
Research paper

Innate immune antagonism of mosquito-borne flaviviruses in humans and mosquitoes

Mosquito-borne viruses of the Flavivirus genus ( Flaviviridae family) pose an ongoing threat to global public health. For example, dengue, Japanese encephalitis, West Nile, yellow fever, and Zika viruses are transmitted by infected mosquitoes and cause severe and fatal…
Read more
default publication image
Research paper

Innate immune antagonism of mosquito-borne flaviviruses in humans and mosquitoes

Mosquito-borne viruses of the Flavivirus genus ( Flaviviridae family) pose an ongoing threat to global public health. For example, dengue, Japanese encephalitis, West Nile, yellow fever, and Zika viruses are transmitted by infected mosquitoes and cause severe and fatal…
Read more
default publication image
Research paper

First genomic evidence of dual African swine fever virus infection: case report from recent and historical outbreaks in Sardinia

African swine fever virus (ASFV) is one of the pathogens of highest concern worldwide. Despite different virus lineages co-circulating in several areas, dual infections in the same animal have been rarely observed, suggesting that ASF superinfections are infrequent events…
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default publication image
Research paper

Ongoing assessment of the molecular evolution of peste des petits ruminants virus continues to question viral origins

Understanding the evolution of viral pathogens is critical to being able to define how viruses emerge within different landscapes. Host susceptibility, which is spread between different species and is a contributing factor to the subsequent epidemiology of a disease, is…
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