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Coronavirus RNA synthesis takes place within membrane-bound sites

Infectious bronchitis virus (IBV), a gammacoronavirus, is an economically important virus to the poultry industry, as well as a significant welfare issue for chickens. As for all positive strand RNA viruses, IBV infection causes rearrangements of the host cell intracellular…

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Coronavirus RNA synthesis takes place within membrane-bound sites

Infectious bronchitis virus (IBV), a gammacoronavirus, is an economically important virus to the poultry industry, as well as a significant welfare issue for chickens. As for all positive strand RNA viruses, IBV infection causes rearrangements of the host cell intracellular…

default publication image

Marek's disease virus modulates T cell proliferation via activation of cyclooxygenase 2-dependent prostaglandin E2

Marek's disease virus (MDV), an avian alphaherpesvirus, infects chickens, transforms CD4+ T cells, and induces immunosuppression early during infection. However, the exact mechanisms involved in MDV-induced immunosuppression are yet to be identified. Here, our results…

Coronavirus particle illustrated in red

Clues about coronavirus replication in host cells uncovered by Pirbright scientists

More clues about coronavirus replication in humans and animals have been uncovered by researchers at Pirbright. This research fills in important knowledge gaps that could help to control disease caused by a range of coronaviruses in the future. When we think of coronaviruses…

Coronavirus particle illustrated in red

Clues about coronavirus replication in host cells uncovered by Pirbright scientists

More clues about coronavirus replication in humans and animals have been uncovered by researchers at Pirbright. This research fills in important knowledge gaps that could help to control disease caused by a range of coronaviruses in the future. When we think of coronaviruses…

Chickens scratching in grass

Avian influenza: tackling large numbers of outbreaks this winter in the UK

Nearly two years on, the COVID-19 pandemic is still dominating the news and continues to cause concern for populations across the globe. However, UK poultry and wild bird populations are currently facing their own health threat. We are not the only ones that have faced…

Herd of goats

Pirbright research develops new vaccines that could contribute to the global eradication of peste des petits ruminants virus

Two new vaccine candidates that could differentiate between vaccinated and infected animals and contribute to the ongoing global eradication of peste des petits ruminants virus (PPRV) have been developed by researchers at The Pirbright Institute. Following the successful…

Two women on a lecture theatre stage (one with a face covering) holding a framed picture and glass trophy

Pirbright wins Openness Award for internal engagement activities on animal research

On Monday 6 December, The Pirbright Institute won the Internal Engagement category at the eighth annual Understanding Animal Research (UAR) Openness Awards for its exemplary approach to internal engagement practices, and its joined-up approach to research to ensure clarity…

Plowright and Jenner buildings at Pirbright against a blue sky

Funding strengthens Pirbright and Glasgow Centre for Virus Research partnership

The long-term partnership between The Pirbright Institute and MRC-University of Glasgow Centre for Virus Research (CVR) has been strengthened by a joint funding award of £500,000 from the Biotechnology and Biological Sciences Research Council (BBSRC). Pirbright and the CVR…

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Complete genome sequencing of field isolates of peste des petits ruminants virus from Tanzania revealed a high nucleotide identity with lineage III PPR viruses

Peste des petits ruminants virus (PPRV) causes a highly devastating disease of sheep and goats that threatens food security, small ruminant production and susceptible endangered wild ruminants. With policy directed towards achieving global PPR eradication, the establishment…