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A replication-competent foot-and-mouth disease virus expressing a luciferase reporter

Bioluminescence is a powerful tool in the study of viral infection both in vivo and in vitro. Foot-and-mouth disease virus (FMDV) has a small RNA genome with a limited tolerance to foreign RNA entities. There has been no success in making a reporter FMDV expressing a…

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Hyalomma ticks on northward migrating birds in southern Spain: Implications for the risk of entry of Crimean-Congo haemorrhagic fever virus to Great Britain

Crimean-Congo haemorrhagic fever virus (CCHFV) is a zoonotic virus transmitted by Hyalomma ticks, the immature stages of which may be carried by migratory birds. In this study, a total of 12 Hyalomma ticks were recovered from five of 228 migratory birds trapped in Spring…

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Marek's disease virus infection of phagocytes: a de novo in vitro infection model

Marek's disease virus (MDV) is an alphaherpesvirus that induces T-cell lymphomas in chickens. Natural infections in vivo are caused by the inhalation of infected poultry house dust and it is presumed that MDV infection is initiated in the macrophages from where the infection…

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Immune escape variants of H9N2 influenza viruses containing deletions at the haemagglutinin receptor binding site retain fitness in vivo and display enhanced zoonotic characteristics

H9N2 avian influenza viruses are enzootic in poultry across Asia and North Africa where they pose a threat to human health, both as zoonotic agents and as potential pandemic candidates. Poultry vaccination against H9N2 viruses has been employed in many regions, however…

Pirbright scientist wins prestigious poultry research award

Dr. Vishi Reddy, a post-doctoral scientist at The Pirbright Institute, has been awarded the prestigious 2017 High Quality Poultry Science Award, by global animal health company, MSD Animal Health. Taking place at the recent 2017 MSD Animal Health High Quality Poultry…

Two calves in high containment. They are licking the door frame.

New website gives unique public access to Pirbright’s animal facilities

A new website launched today (14 June) provides unique access to the animal research facilities at The Pirbright Institute which support its world-leading scientific research into livestock viral diseases and helps save countless animal and potentially human lives, globally…

Pirbright partnership to lead newly funded international veterinary network

The Pirbright Institute has joined with The Roslin Institute to launch an International Veterinary Vaccinology Network (IVVN) following their successful £2.1m joint funding bid. Grant funded by the Medical Research Council* and the Biotechnology and Biological Sciences…

Chicken immune system could hold key to protect poultry and humans from viruses

Newly discovered components of the chicken innate immune system suggest poultry may be better equipped to fight viruses than scientists previously thought. Researchers from The Pirbright Institute investigating chicken immunology, have discovered a previously unknown…

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Swine vesicular disease diagnostic reagents

Inactivated antigen and SVD Reference Sera.