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Foot-and-mouth disease diagnostic reagents

Bovine control serum, rabbit and guinea pig sera, inactivated antigens, NSP panel, ELISA kits, monoclonal antibodies.

UK study of mosquito feeding habits shows some species more choosy than others

The largest study of blood feeding by mosquitoes ever conducted in the UK, has revealed that some species are more selective than others when choosing a host. Researchers aimed to discover which birds and mammals mosquitoes were biting in order to understand the potential…

New insight could lead to improved methods for preventing foot-and-mouth disease

New insight into the process of interaction between foot-and-mouth disease virus (FMDV) and host cells, could lead to the development of anti-virals capable of blocking the virus from entering cells and preventing infection. The research, a national and international…

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Rules of engagement between αvβ6 integrin and foot-and-mouth disease virus

Foot-and-mouth disease virus (FMDV) mediates cell entry by attachment to an integrin receptor, generally alphavbeta6, via a conserved arginine-glycine-aspartic acid (RGD) motif in the exposed, antigenic, GH loop of capsid protein VP1. Infection can also occur in tissue…

New research on sex determination in mosquitoes could transform disease control

Scientists at The Pirbright Institute believe a newly funded study will provide crucial answers to the process behind sex determination in mosquitoes and could have a game-changing impact on the control of these insect pests and potentially other insects too. The research…

Peste des petits ruminants is a neglected disease which now poses a threat to Europe

Better coordinated vaccine strategies are urgently needed to combat the spread of peste des petits ruminants (PPR); a neglected but devastating livestock disease which now poses a threat to sheep and goat populations in Europe, say scientists from The Pirbright Institute…

New model determining vectors for bluetongue and Schmallenberg will help control outbreaks

A new model developed by scientists at The Pirbright Institute has enabled researchers to determine the method of transmission for bluetongue and Schmallenberg viral diseases for the first time, which they believe will significantly improve efforts to control disease…

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Changes to taxonomy and the International Code of Virus Classification and Nomenclature ratified by the International Committee on Taxonomy of Viruses (2017)

This article lists the changes to virus taxonomy approved and ratified by the International Committee on Taxonomy of Viruses (ICTV) in March 2017.

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Peste des petits ruminants (PPR): A neglected tropical disease in Maghreb region of North Africa and its threat to Europe

Peste des petits ruminants (PPR) is a contagious disease listed by the World Organisation for Animal health (OIE) as being a specific hazard. It affects sheep, goats, and wild ungulates, and is prevalent throughout the developing world particularly Asia, the Middle East, and…

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Structural insight into African swine fever virus A179L mediated inhibition of apoptosis

Programmed cell death is a tightly controlled process critical for the removal of damaged or infected cells. Pro- and anti-apoptotic proteins of the Bcl-2 family are pivotal mediators of this process. African Swine Fever virus (ASFV) is a large DNA virus, the only member of…