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The Houghton Facility

A facility to hatch and raise poultry under sterile conditions.

BBSRC National Vaccinology Centre: The Jenner Building

The BBSRC National Vaccinology Centre: The Jenner Building

A state-of-the-art low-containment facility supporting vital research on endemic poultry and livestock viruses, immunology, and genomics.

Gene editing

Pirbright research to boost vaccine production

Scientists at The Pirbright Institute have received money which will enable research into boosting vaccine yields by up to ten fold. The funding was awarded by the Livestock Vaccine Innovation Fund which is supported by the Bill & Melinda Gates Foundation (BMGF), Global…

Plowright Building

The BBSRC National Virology Centre: The Plowright Building

A state-of-the-art, high containment laboratory for researching high-risk, exotic and zoonotic viruses.

The Plowright Building

Facilities and resources

Explore our specialist science facilities, cutting-edge technology platforms, and request services like diagnostic testing.

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Modulation of type I interferon signaling by African swine fever virus (ASFV) of different virulence L60 and NHV in macrophage host cells

ASFV causes an important disease of domestic swine and wild boar. Currently no vaccine is available, highlighting the necessity to understand ASFV modulation of innate immune responses in natural host cells. With this aim, macrophage cultures enriched in SWC9 and CD163…

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NDV entry into dendritic cells through macropinocytosis and suppression of T lymphocyte proliferation

Newcastle disease virus (NDV) causes major economic losses in the poultry industry. Previous studies have shown that NDV utilizes different pathways to infect various cells, including dendritic cells (DCs). Here, we demonstrate that NDV gains entry into DCs mainly via…

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The phylogenetic analysis of VP1 genomic region in foot-and-mouth disease virus serotype O isolates in Sri Lanka reveals the existence of 'Srl-97', a newly named endemic lineage

Foot and mouth disease (FMD) has devastated the cattle industry in Sri Lanka many times in the past. Despite its seriousness, limited attempts have been made to understand the disease to ameliorate its effects-current recommendation for vaccines being based solely on…

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ICTV virus taxonomy profile: Asfarviridae

The family Asfarviridae includes the single species African swine fever virus, isolates of which have linear dsDNA genomes of 170-194 kbp. Virions have an internal core, an internal lipid membrane, an icosahedral capsid and an outer lipid envelope. Infection of domestic pigs…

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Population dynamics of engineered underdominance and killer-rescue gene drives in the control of disease vectors

Vector-borne diseases represent a severe burden to both human and animal health worldwide. The methods currently being used to control a range of these diseases do not appear sufficient to address the issues at hand. As such, alternate methods for the control of vector-borne…