Search | The Pirbright Institute

Filters

default publication image

Thapsigargin Is a broad-spectrum inhibitor of major human respiratory viruses: coronavirus, respiratory syncytial virus and influenza A virus

The long-term control strategy of SARS-CoV-2 and other major respiratory viruses needs to include antivirals to treat acute infections, in addition to the judicious use of effective vaccines. Whilst COVID-19 vaccines are being rolled out for mass vaccination, the modest…

default publication image

Development and validation of confirmatory foot-and-mouth disease virus antibody ELISAs to identify infected animals in vaccinated populations

In foot-and-mouth disease (FMD)-endemic countries, vaccination is commonly used to control the disease, whilst in FMD-free countries, vaccination is considered as an option, in addition to culling the infected and in contact animals. FMD vaccines are mainly comprised of…

default publication image

The detection of long-lasting memory foot-and-mouth disease (FMD) virus -serotype O-specific CD4(+) T cells from FMD vaccinated cattle by bovine major histocompatibility complex class II tetramer

Foot-and-mouth disease (FMD) is a highly contagious, economically devastating disease of cloven-hooved animals. The development of long-lasting effective FMD vaccines would greatly benefit the global FMD control programme. Deep analysis of adaptive immunity in cattle…

default publication image

The detection of long-lasting memory foot-and-mouth disease (FMD) virus -serotype O-specific CD4(+) T cells from FMD vaccinated cattle by bovine major histocompatibility complex class II tetramer

Foot-and-mouth disease (FMD) is a highly contagious, economically devastating disease of cloven-hooved animals. The development of long-lasting effective FMD vaccines would greatly benefit the global FMD control programme. Deep analysis of adaptive immunity in cattle…

default publication image

A field study evaluating the humoral immune response in Mongolian sheep vaccinated against sheeppox virus

Sheeppox is a transboundary disease of small ruminants caused by infection with the capripoxvirus sheeppox virus (SPPV). Sheeppox is found in Africa, the Middle East and Asia and is characterised by fever, multifocal cutaneous raised lesions, and death. Vaccination with live…

default publication image

A field study evaluating the humoral immune response in Mongolian sheep vaccinated against sheeppox virus

Sheeppox is a transboundary disease of small ruminants caused by infection with the capripoxvirus sheeppox virus (SPPV). Sheeppox is found in Africa, the Middle East and Asia and is characterised by fever, multifocal cutaneous raised lesions, and death. Vaccination with live…

Marek’s disease (MD): eLearning

Learn about Marek's disease pathogenesis, diagnostics, and control strategies.

Kerry Newbrook (left) and Nazia Thakur (right)

Two Pirbright scientists win Microbiology Society prizes

Two scientists from The Pirbright Institute have been awarded the Journal of General Virology - Most Promising Science prize for their poster presentations at this year’s Microbiology Society Annual Conference. Their achievements are testament to the incredibly important…

Ten years rinderpest free

Ten years on: Celebrating the eradication of rinderpest

Today the world celebrates ten years since rinderpest virus was officially declared eradicated on 25 May 2011 by the World Organisation for Animal Health (OIE). This achievement particularly resonates with the goals and history of The Pirbright Institute, whose staff both…

default publication image

Development and validation of a mucosal antibody (IgA) test to identify persistent infection with foot-and-mouth disease virus

It is well known that approximately 50% of cattle infected with foot-and-mouth disease (FMD) virus (FMDV) may become asymptomatic carrier (persistently infected) animals. Although transmission of FMDV from carrier cattle to naÃ¯ve cattle has not been demonstrated…