The History of The Pirbright Institute
The Pirbright Institute has been in existence for over 100 years and in 2014 celebrated its Centenary. It was first established as a cattle testing station for tuberculosis in 1914 and has developed over the years to become one of the UK's leading virus diagnostics and surveillance centres and is now also at the forefront of virus research. The recent development of the site to incorporate a state-of-the-art high containment (SAPO 4) laboratory – the BBSRC National Virology Centre: The Plowright Building has enabled a unique combination of fundamental and applied research into pathogenic diseases with potentially devasting impact.
The Institute's achievements over the past century have been many and varied but throughout this time it has continued to play a pivotal role in controlling and preventing some of the world's most devastating diseases with the development of new and improved diagnostics and vaccines.
100 Years of Excellence
Pirbright is established as a cattle testing station for tuberculosis.
The cattle testing station becomes the Pirbright Experimental Station for the Foot-and-Mouth Disease Research Committee and research on the disease (FMD) begins with first experiments on large animals.
Pirbright becomes the sole UK centre for research on foot-and-mouth disease.
With the appontment of a full time Director of research, Pirbright is renamed the Foot-andMouth Disease Research Institute.
First ultracentrifugation and purification of foot-and-mouth diseases particles.
Pirbright is designated as the FAO World Reference Laboratory for Foot-and-Mouth disease virus (FMDV).
The Institute is renamed the Animal Virus Research Institute and research begins into other viral diseases which are considered a threat to the UK including bluetongue, swine vesicular disease and rinderpest.
Pirbright plays a major role in the control and eradication of a foot-and-mouth disease outbreak in the UK, the crisis led to the slaughter of 430,000 animals across more than 2,000 farms.
Midge colonies are established at pirbright for studies on viruses that are transmitted by insect vectors (such as bluetongue).
A new vaccine for peste des petit ruminants, a highly contagious disease affecting goats and sheep, is developed and validated.
The Institute of Animal Health is formed by bringing together The Animal Virus Research Institute at Pirbright, the Houghton Poultry Research Station in Cambridgeshire, the Neuropathogenesis Unit (NPU) in Edinburgh and the Institute for the Research on Animal Diseases at Compton (Berkshire). The NPU retains its name while the other three are known as the Compton, Houghton and Pirbright Laboratories.
The NPU plays a vital role in the control in the UK epidemic of bovine spongiform encephalopathy (BSE).
Houghton Laboratory is closed and all poultry research is moved to new facilities at Compton.
Pirbright is designated as the FAO World Reference Laboratory for rinderpest.
The structure of bluetongue virus is revealed through x-ray crystallography.
Pirbright plays a vital role in the control of another major outbreak of foot-and-mouth disease in the UK. The 2001 crisis cost the UK economy an estimated £8 billion.
The NPU becomes part of The Roslin Institute in Edinburgh. Pirbright substantially contributes to the eradication of bluetongue following an outbreak in the UK, saving the economy £450 million.
Phase 1 of the redevelopment of the Pirbright site commences: construction of a new hi-containment (CL4) laboratory complex begins.
FAO announces the global eradication of rinderpest in which Pirbright plays a major role, saving the African economy alone around £1 billion a year.
Phase 2 of the Pirbright site redevelopment gets the green light from government: new lower containment laboratories (CL2) and a Biological Resources Facility (BRF). The Institute for Animal Health is renamed and rebranded The Pirbright Institute.
A new type of FMDV vaccine is developed using synthetically produce protein shells of the virus. It is more stable than current vaccines and can also be produced outside of high bio-containment facilities as it does not contain live virus.
The construction phase of the new high containment laboratories the BBSRC National Virology Centre: The Plowright Building is completed on time and on budget and is opened by the then Secretary of State for BIS Vince Cable in October. Work begins on the lower containment laboratories.
Looking to the future
In 2015 the Institute has celebrated the move into the BBSRC National Virology Centre, a consolidation of research from two sites (one at Compton in Berkshire) to one at Pirbright and significant steps forward in the development of vaccines against diseases such as foot-and-mouth, African swine fever and swine influenza. New world-class facilities attract eminent researchers from around the globe to continue our mission of excellent research and surveillance of viral diseases of farm animals and viruses that spread from animals to humans.