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Cattle being herded

Tools to assess the performance of FMD vaccines – driving improvements in quality

Despite widespread use of inactivated vaccines to control foot-and-mouth disease (FMD), there is no systematic approach to demonstrate the regional relevance of products against the specific serotypes and strains that circulate in endemic countries in Africa and Asia. A…

This scanning electron microscope image shows SARS-CoV-2 (yellow)—also known as 2019-nCoV, the virus that causes COVID-19—isolated from a patient in the U.S., emerging from the surface of cells (pink) cultured in the lab.

Pirbright begins testing new coronavirus vaccines on animals to help combat COVID-19

The Pirbright Institute is joining in the global battle to help control COVID-19 by using its unique expertise and facilities to support the development of vaccines to protect against severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the cause of the current…

Very large and close group of cattle in India. They all have horns

Scientists pioneer ‘early warning’ analysis for foot-and-mouth disease

A novel lineage of foot-and-mouth disease virus (FMDV) can have severe socio-economic impacts in Asia. Researchers at the FAO World Reference Laboratory for FMD (WRLFMD), based at The Pirbright Institute, have tracked an emerging FMDV lineage in the Middle East. Writing in…

Influenza antibodies made by Pirbright reduce disease in chickens

Scientists at The Pirbright Institute have engineered synthetic antibody molecules that can be administered to poultry to reduce the symptoms of influenza, as well as decreasing the amount of influenza virus they shed into the environment. These results suggest that there is…

An empty CL3 laboratory at The Pirbright Institute. There are three Biological safety cabinets, two of which have yellow gloves that go into the cabinet

Launch of the Biorisk Advisor Training course

A new training course developed at The Pirbright Institute has been approved by the Royal Society of Biology (RSB) for continuing professional development (CPD) purposes. This approval recognises and underscores its relevance and value to those in the field and marks a…

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Exploiting Viral DNA Genomes to Explore the Dispersal History of African Swine Fever Genotype II Lineages in Europe.

African swine fever virus (ASFV) is a highly virulent DNA virus that causes African swine fever, a severe hemorrhagic disease affecting domestic and wild pigs, leading to significant animal health burdens and economic losses. Initially limited to the sub-Saharan African…

Pirbright confirms African horse sickness outbreak in Thailand

Scientists in the Non-Vesicular Reference Laboratory (NVRL) at The Pirbright Institute have confirmed an outbreak of African horse sickness (AHS) in Thailand. AHS is the most lethal viral disease of horses known and the rapid diagnostic services provided by Pirbright has…

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Swine influenza A virus infection sets the local immunological landscape in subsequent infection with porcine reproductive and respiratory syndrome virus

Farmed pigs are frequently exposed to respiratory infections, with swine influenza A virus (swIAV) and porcine reproductive and respiratory syndrome virus (PRRSV) being key drivers. Most co-infection studies with these viruses have focused on PRRSV infection followed by…

Pirbright supports UK’s effort to ramp up diagnostic testing for COVID-19

The Pirbright Institute, which is home to several World Reference Laboratories for viral diseases of livestock, is using its equipment and expertise in diagnostics and disease surveillance to support COVID-19 testing in the UK. The Institute is helping in three key areas…

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Pexophagy-driven redox imbalance promotes virus-induced ferroptosis

Peroxisomes are critical organelles that maintain cellular redox homeostasis. Many viruses induce oxidative stress and degrade peroxisomes, but the mechanisms and consequences remain unclear. In this study, we systematically investigate how virus-induced pexophagy regulates…