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A method for assessing the vectorial competence of field collected Culicoides spp. for bluetongue virus. (Letter)

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LRRfinder: a web application for the identificationC of leucine-rich repeats and an integrative Toll-like receptor database

Homology modelling is considered the most accurate technique for computational prediction of protein structure. However, this technique comes with fundamental caveats of dependency on template quality, identification of structural features and accuracy of alignment. Leucine…

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Regulation of a bovine nonclassical major histocompatibility complex class I gene promoter

Studies have shown in humans and other species that the major histocompatibility complex class I (MHC-I) region is involved at a number of levels in the establishment and maintenance of pregnancy. The aim of this study was to characterize how a bovine nonclassical MHC-I gene…

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Colostral antibody protection and interference with immunity in lambs born from sheep vaccinated with an inactivated bluetongue serotype 8 vaccine

Widespread vaccination programmes against Bluetongue virus serotype 8 (BTV-8), using inactivated vaccines, are being carried out across many countries in northern, western and southern Europe. This study investigates the extent and length of colostral antibody protection, as…

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Treatment of horses with cypermethrin against the biting flies Culicoides nubeculosus, Aedes aegypti and Culex quinquefasciatus

An in vitro assay was used to assess the efficacy of the proprietary pyrethroid insecticide cypermethrin applied to horses (Deosect spray, 5.0%, w/v Fort Dodge Animal Health) against the biting midge Culicoides nubeculosus (Meigen) (Diptera: Ceratopogonidae) and the…

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Expression profiling of genes associated with regulatory functions of T-cell subsets in Marek's disease virus-infected chickens

The environment of tumours caused by Marek's disease virus (MDV) in chickens has been shown to have an immunoregulatory phenotype. The objective of the present study was to examine the expression of key T-regulatory markers during various stages of MDV pathogenesis. Specific…

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Recent spread of foot-and-mouth disease in the Far East

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Qualitative assessment of the commodity risk for spread of foot-and-mouth disease associated with international trade in deboned beef

The risk of importing foot-and-mouth disease virus (FMDV) restricts trade in livestock and their products from parts of the world where the virus is present. This reduces trade opportunities and investment in the livestock sector of many developing countries and constrains…

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Fucosylation enhances colonization of ticks by Anaplasma phagocytophilum

Fucosylated structures participate in a wide range of pathological processes in eukaryotes and prokaryotes. The impact of fucose on microbial pathogenesis, however, has been less appreciated in arthropods of medical relevance. Thus, we used the tick-borne bacterium Anaplasma…

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Differential distribution of WC1(+) gammadelta TCR(+) T lymphocyte subsets within lymphoid tissues of the head and respiratory tract and effects of intranasal M. bovis BCG vaccination

BCG vaccination of neonatal calves induces significant protection against bovine tuberculosis. The enhanced protection observed in neonatal calves may be linked to an enhanced capacity for IFN? production by innate cells, including WC1+ ?? T cells, which constitute a major…