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Germline transformation of the West Nile virus and avian malaria vector Culex quinquefasciatus Say using the piggyBac transposon system

Culex quinquefasciatus Say is a mosquito which acts as a vector for numerous diseases including West Nile virus, lymphatic filariasis and avian malaria, over a broad geographical range. As the effectiveness of insecticidal mosquito control methods declines, the need has…

A group of 17 white goats with black patches. Some are lying down, some are standing. On the right are three people in green scrubs holding clipboards and bottled water. A small tree trunk separates the goats and people. Above are the leaves of a tree

Field study reveals the best way of sampling for foot-and-mouth disease in endemic settings

Scientists from The Pirbright Institute have led a longitudinal study of foot-and-mouth disease (FMD) in collaboration with the National Veterinary Research Institute (NVRI) in Northern Nigeria. The project investigated the role that small ruminants and contaminated…

A group of 17 white goats with black patches. Some are lying down, some are standing. On the right are three people in green scrubs holding clipboards and bottled water. A small tree trunk separates the goats and people. Above are the leaves of a tree

Field study reveals the best way of sampling for foot-and-mouth disease in endemic settings

Scientists from The Pirbright Institute have led a longitudinal study of foot-and-mouth disease (FMD) in collaboration with the National Veterinary Research Institute (NVRI) in Northern Nigeria. The project investigated the role that small ruminants and contaminated…

Female presenter in front of audience and backdrop of meeting programme shown on screen

Sustainability takes centre stage at inaugural UK Lab Management Biosciences Conference

The inaugural UK Lab Management Biosciences Conference took place on Thursday 20 March 2025, at the Mandolay Hotel in Guildford, Surrey. Organised by colleagues from The Pirbright Institute and London School of Hygiene and Tropical Medicine, this event brought together…

Close up of the face of a pink pig with brown patches. Its head is resting on the straw

Rolling in the straw: Pigging out on enrichment at Pirbright

Find out how we keep our pigs engaged.

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Deletion of B125R increases protection induced by a genotype II African swine fever vaccine candidate.

A modified live attenuated African swine fever genotype II virus, GΔDKE-CmutQ96R/K108D, with deletions of three genes, DP148R, EP153R, and K145R and expressing a mutated CD2v protein with a non-haemadsorbing phenotype, was further modified by first removing two reporter gene…

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Deletion of B125R increases protection induced by a genotype II African swine fever vaccine candidate.

A modified live attenuated African swine fever genotype II virus, GΔDKE-CmutQ96R/K108D, with deletions of three genes, DP148R, EP153R, and K145R and expressing a mutated CD2v protein with a non-haemadsorbing phenotype, was further modified by first removing two reporter gene…

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Phylogeny of multiple genomic regions of infectious laryngotracheitis virus in Turkish poultry flocks

Infectious laryngotracheitis (ILT) is an economically significant respiratory tract viral disease affecting poultry worldwide. There is a scarcity of data on the types of ILTV strains circulating in Turkey. This study aimed to determine the frequency and genotypic variations…

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Cross-protectivity of henipavirus soluble glycoprotein in an in vivo model of Nipah virus disease

Introduction: Nipah virus (NiV) is one of a group of highly pathogenic viruses classified within the Henipavirus genus. Since 2012 at least 11 new henipa-like viruses have been identified, including from new locations and reservoir hosts; the pathogenicity of these new…

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The efficacy of vector-proof accommodation for the protection of livestock against Culicoides biting midges

Background Bluetongue virus serotype 3 emerged in northern Europe and the UK for the first time in 2023, causing significant losses of domestic ruminants. Vector-proof accommodation is considered a potential control measure to reduce host-vector contact, but this has not…