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A conserved glutathione binding site in poliovirus is a target for antivirals and vaccine stabilisation

Strategies to prevent the recurrence of poliovirus (PV) after eradication may utilise non-infectious, recombinant virus-like particle (VLP) vaccines. Despite clear advantages over inactivated or attenuated virus vaccines, instability of VLPs can compromise their…

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Development of in house ELISAs to detect antibodies to SARS-CoV-2 in infected and vaccinated humans by using recombinant S, S1 and RBD proteins

Background: The aim of this study was to produce in-house ELISAs which can be used to determine SARS-CoV-2-specific antibody levels directed against the spike protein (S), the S1 subunit of S and the receptor binding domain (RBD) of S in SARS-CoV-2 vaccinated and infected…

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The immune response to lumpy skin disease virus in cattle is influenced by inoculation route

Lumpy skin disease virus (LSDV) causes severe disease in cattle and water buffalo and is transmitted by hematophagous arthropod vectors. Detailed information of the adaptive and innate immune response to LSDV is limited, hampering the development of tools to control the…

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Predicting cross-protection against foot-and-mouth disease virus strains by serology after vaccination

Serology is widely used to predict whether vaccinated individuals and populations will be protected against infectious diseases, including foot-and-mouth disease (FMD), which affects cloven-hoofed animals. Neutralising antibody titres to FMD challenge viruses correlate to…

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Predicting cross-protection against foot-and-mouth disease virus strains by serology after vaccination

Serology is widely used to predict whether vaccinated individuals and populations will be protected against infectious diseases, including foot-and-mouth disease (FMD), which affects cloven-hoofed animals. Neutralising antibody titres to FMD challenge viruses correlate to…

Maria receiving award from person in front of blue screen

Visiting Pirbright researcher wins L’Oréal-UNESCO award

Dr Mariatulqabtiah Abdul Razak, a visiting scientist in Pirbright’s Avian Influenza Group, has been awarded the prestigious L’Oréal-UNESCO For Women in Science Award 2022 (Malaysia programme). Maria, an Associate Professor in the Department of Cell and Molecular Biology at…

Testimonials

Please see below some comments from previous learners about our courses. “It was very helpful and informative.” Veterinary vaccine development process eLearning course “The courses were well organized and simplified.” Peste des petits ruminants eLearning course “A very user…

The Pirbright Institute welcomes two new Trustee Board members

As a registered charity and an independent company, The Pirbright Institute is governed by a Board of non-executive Trustee Directors. The Institute has appointed two new Trustees for 2022: Professor Deenan Pillay and Professor Mike Turner. The new Trustees are joining the…

HEPA Deck at the Pirbright Institute

HEPA Filtration - validation, testing and changing: Instructor-led

Learn about HEPA filters and how to test and validate them.

Infectious bursal disease (IBD): eLearning

Learn about infectious bursal disease virus, how it spreads and the clinical signs.