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Genomic analysis of putative hybrids between Potamochoerus spp. and domestic pigs from sympatric areas in West Africa and Madagascar

In many rural areas of sub-Saharan Africa and Madagascar, domestic pigs (DPs, Sus scrofa domesticus) can coexist in sympatry, with species of the genus Potamochoerusspp. ( P. larvatusor P. porcus). Reports of hybridization between domestic pigs and these two wild suid…

Build the Future – Celebrating 15 years of National Apprenticeship Week

This week marks the 15th anniversary of National Apprenticeship Week, a week-long celebration of apprenticeships from 7 - 13 February 2022, shining a light on the positive impact that apprenticeships make to individuals, businesses and the wider economy. Thanks to The…

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Heart-nosed bat alphacoronaviruses use human CEACAM6 to enter cells

Abstract Identifying viruses with zoonotic potential on the basis of their ability to enter human cells is a critical component of pandemic prediction, prevention and preparedness. Here using a computational approach that retains maximum phylogenetic diversity, we selected…

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Conserved Linear Epitopes in the VP1 Protein of Foot‐and‐Mouth Disease Virus Serotype SAT2: Identification and Characterization

Foot‐and‐mouth disease virus (FMDV) serotype Southern African Territories 2 (SAT2), historically endemic to sub‐Saharan Africa, has recently expanded its geographical range to the Middle East, posing a significant transboundary threat to global livestock industries…

Sir John Kingman unveilling the brick bull in celebration of WLRFMD 60 years

In memoriam: Professor John Stephenson, Chair of Pirbright’s Trustee Board

It is with great sadness that we announce the unexpected passing last weekend of Professor John Stephenson, Chair of The Pirbright Institute’s Board of Trustees. Professor Stephenson served as a Pirbright Trustee for five years before becoming the Chair of the Trustee Board…

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Performance of prototype serological immunoassays for foot-and-mouth disease virus using G-H loop peptides and stabilized virus-like particles

ABSTRACT Inter-serotype cross-reactivity of foot-and-mouth disease (FMD) antibody enzyme-linked immunosorbent assays (ELISAs) can exceed 50%, leading to incorrect serotyping of outbreaks with implications for vaccine selection. In this study, synthetic peptides that mimic…

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Mapping hemagglutinin residues driving antigenic diversity in H5Nx avian influenza viruses

ABSTRACT Since its emergence in 1996, the H5 avian influenza virus (AIV) A/Goose/Guangdong/1/1996 (Gs/GD) hemagglutinin (HA) has evolved into over 30 genetically and antigenically distinct clades, including the widespread clade 2.3.4.4b. Vaccination is widely used in endemic…

Scientist in a white lab coat

Pirbright celebrates our female scientists on International Day of Women and Girls in Science

11 February 2022 marks the 7th International Day of Women and Girls in Science. To highlight the important contribution our female scientists have made both to the Institute and to our global research in protecting animal and human health, we have been speaking to them about…

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Oropouche virus: transmission, epidemiology, genetic diversity, and public health implications

Historically endemic to parts of South America, Oropouche virus (OROV) has caused an estimated 500,000 infections since its discovery, with a marked geographic expansion beyond the Amazon basin into other regions of South America and the Caribbean since late 2023. This…

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The changing landscape of bluetongue in northern Europe

Abstract Bluetongue was historically a disease of the tropics and subtropics, but over the past 20 yr has emerged in temperate regions such as northern Europe. Multiple serotypes of bluetongue virus (BTV) have been introduced into northern Europe, with some becoming enzootic…