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Activation of dendritic cells in tonsils is associated with CD8 T cell responses following vaccination with live attenuated classical swine fever virus

Classical swine fever (CSF) is a highly contagious disease caused by the classical swine fever virus (CSFV). The live attenuated C-strain vaccine is highly efficacious, initiating protection within several days of delivery. The vaccine strain is detected in the tonsil early…

Buffalo and calf

New research giving insight into the persistence of highly contagious foot-and-mouth disease virus features on front cover of Science Magazine

A major new study, featured on the cover of Science Magazine today (1 October 2021), undertaken by scientists at The Pirbright Institute, Oregon State University, Onderstepoort Veterinary Institute and SANParks, Veterinary Wildlife Services, Kruger National Park explores the…

Buffalo and calf

New research giving insight into the persistence of highly contagious foot-and-mouth disease virus features on front cover of Science Magazine

A major new study, featured on the cover of Science Magazine today (1 October 2021), undertaken by scientists at The Pirbright Institute, Oregon State University, Onderstepoort Veterinary Institute and SANParks, Veterinary Wildlife Services, Kruger National Park explores the…

Coronavirus particle (red) infecting a human cell (blue)

Pirbright contributes to new global coronavirus research and innovation network

The UK International Coronavirus Network (UK-ICN) is a new global network of researchers from both animal and human coronavirus communities. The COVID-19 pandemic has shown what a huge impact a zoonotic disease can have globally. With the current death toll from the COVID-19…

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A Global Media Analysis of the Impact of the COVID-19 Pandemic on Chicken Meat Food Systems: Key Vulnerabilities and Opportunities for Building Resilience

Food systems are increasingly under threat, with climate, biological, economic or policy shocks and stressors occurring at an increasing frequency and scale. Their complex and fragile nature has become even more apparent during the COVID-19 pandemic. A systematic review of…

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GAMUT: A genomics big data management tool

Efficient analysis of Single Nucleotide Polymorphisms (SNPs) across genomic samples enable in deciphering the relationship between genotype and phenotype. The core principle behind SNP comparison is to arrive at a probable list of variants that can differentiate two sets of…

Culex quinquefasciatus (southern house mosquitoes) adult females, expressing red fluorescent protein on left and WT on the right

Pirbright scientists show gene editing tool could crack down on diseases spread by southern house mosquitoes

A new gene editing tool has been successfully applied to the southern house mosquito by researchers at The Pirbright Institute. This paves the way for genetic control methods that could prevent the mosquito from spreading human and animal diseases. The female southern house…

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Elimination of non-cytopathic bovine viral diarrhea virus from the LFBK-αvβ6 cell line

The LFBK-αvβ6 cell line is highly sensitive for the isolation of foot-and-mouth disease virus (FMDV) and porcinophilic vesicular viruses. However, LFBK-αvβ6 cells are contaminated with a non-cytopathic bovine viral diarrhea virus (BVDV), which complicates handling procedures…

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Environmental sampling for the detection of foot-and-mouth disease virus and peste des petits ruminants virus in a live goat market, Nepal

Livestock markets are considered vital parts of the agricultural economy, particularly in developing countries where livestock keeping contributes to both food security and economic stability. Animals from diverse sources are moved to markets, they mix while they are there…

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Environmental sampling for the detection of foot-and-mouth disease virus and peste des petits ruminants virus in a live goat market, Nepal

Livestock markets are considered vital parts of the agricultural economy, particularly in developing countries where livestock keeping contributes to both food security and economic stability. Animals from diverse sources are moved to markets, they mix while they are there…