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The inside of The Philip Mellor Insectary (PMI) at The Pirbright Institute

Science spotlight: Day in the life breeding insects in the Pirbright Philip Mellor Insectary

Dr Melanie Nicholls is a postdoctoral scientist at The Pirbright Institute working in the Philip Mellor Insectary (PMI), a specialist science facility which houses exotic and endemic (native to the UK) insects for use in research on vector-borne viruses. Six bio secure…

Disease Detectives

Have you got what it takes to become a Disease Detective? Pandemic preparedness: why scientists are key Discover how emerging diseases are spread and how research helps to prevent and contain them. Scientists play a critical role in identifying, controlling and preventing…

Flock of brown and white chickens following a person in boots

Pirbright develops new ways to create safe vaccines to protect poultry from infectious bronchitis virus

Researchers from The Pirbright Institute working to improve vaccines for infectious bronchitis virus (IBV) have identified targets in the virus’s genetic code that could make vaccines safer. Better vaccines would have a huge impact on improving health and welfare of poultry…

Flock of brown and white chickens following a person in boots

Pirbright develops new ways to create safe vaccines to protect poultry from infectious bronchitis virus

Researchers from The Pirbright Institute working to improve vaccines for infectious bronchitis virus (IBV) have identified targets in the virus’s genetic code that could make vaccines safer. Better vaccines would have a huge impact on improving health and welfare of poultry…

Inspiring a generation – The Festival of Tomorrow

Last week The Pirbright Institute was back on the road, sharing our science with the public and inspiring potential scientists of the future at the Festival of Tomorrow in Swindon. Bug Busters LEGO mosquito builder The two-day event celebrated the wonders of science and…

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Differential effect of deleting members of African swine fever virus multigene families 360 and 505 from the genotype II Georgia 2007/1 isolate on virus replication, virulence and induction of protection

African swine fever virus multigene family (MGF) 360 and 505 genes have roles in suppressing the type I interferon response and in virulence in pigs, The role of the individual genes is poorly understood. Different combinations of these genes were deleted from the virulent…

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Differential effect of deleting members of African swine fever virus multigene families 360 and 505 from the genotype II Georgia 2007/1 isolate on virus replication, virulence and induction of protection

African swine fever virus multigene family (MGF) 360 and 505 genes have roles in suppressing the type I interferon response and in virulence in pigs, The role of the individual genes is poorly understood. Different combinations of these genes were deleted from the virulent…

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Spatial, temporal and molecular dynamics of swine influenza virus-specific CD8 tissue resident memory T cells

For the first time we have defined naive, central memory, effector memory and differentiated effector porcine CD8 T cells and analyzed their distribution in lymphoid and respiratory tissues after influenza infection or immunization, using peptide-MHC tetramers of three…

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Spatial, temporal and molecular dynamics of swine influenza virus-specific CD8 tissue resident memory T cells

For the first time we have defined naive, central memory, effector memory and differentiated effector porcine CD8 T cells and analyzed their distribution in lymphoid and respiratory tissues after influenza infection or immunization, using peptide-MHC tetramers of three…

default publication image

Spatial, temporal and molecular dynamics of swine influenza virus-specific CD8 tissue resident memory T cells

For the first time we have defined naive, central memory, effector memory and differentiated effector porcine CD8 T cells and analyzed their distribution in lymphoid and respiratory tissues after influenza infection or immunization, using peptide-MHC tetramers of three…