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A pool of eight virally vectored African swine fever antigens protect pigs against fatal disease

Classical approaches to African swine fever virus (ASFV) vaccine development have not been successful; inactivated virus does not provide protection and use of live attenuated viruses generated by passage in tissue culture had a poor safety profile. Current African swine…

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Characterisation of fowl adenovirus (FAdV-8b) strain concerning the geographic analysis and pathological lesions associated with inclusion body hepatitis in broiler flocks in Turkey

Introduction: Fowl adenovirus can cause important diseases in chickens such as inclusion body hepatitis, hepatitis hydropericardium syndrome, and gizzard erosion and ulceration. Inclusion body hepatitis has been regularly reported from many countries. This is the first case…

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Infectious bronchitis virus regulates cellular stress granule signaling

Viruses must hijack cellular translation machinery to express viral genes. In many cases, this is impeded by cellular stress responses. These stress responses result in the global inhibition of translation and the storage of stalled mRNAs, into RNA-protein aggregates called…

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Foot-and-mouth disease surveillance using pooled milk on a large-scale dairy farm in an endemic setting

Pooled milk is used for the surveillance of several diseases of livestock. Previous studies demonstrated the detection of foot-and-mouth disease virus (FMDV) in the milk of infected animals at high dilutions, and consequently, the collection of pooledmilk samples could be…

default publication image

Foot-and-mouth disease surveillance using pooled milk on a large-scale dairy farm in an endemic setting

Pooled milk is used for the surveillance of several diseases of livestock. Previous studies demonstrated the detection of foot-and-mouth disease virus (FMDV) in the milk of infected animals at high dilutions, and consequently, the collection of pooledmilk samples could be…

Infectious bronchitis virus (IBV)

Infectious bronchitis virus shuts down cell stress signals, Pirbright study shows

A new study from scientists at The Pirbright Institute and collaborators at the University of Surrey provides evidence that infectious bronchitis virus (IBV) can regulate the signals involved in the stress response, which would otherwise prevent a virus from making new…

Female pig in hay inside

Pirbright African swine fever vaccine protects 100% of pigs from developing severe disease

Scientists from The Pirbright Institute are a step closer in the race to develop a vital vaccine for African swine fever (ASF). In their recent trial, published in Vaccines, 100 percent of pigs immunised with the new vaccine survived a lethal dose of ASF virus. ASF causes…

Female pig in hay inside

Pirbright African swine fever vaccine protects 100% of pigs from developing severe disease

Scientists from The Pirbright Institute are a step closer in the race to develop a vital vaccine for African swine fever (ASF). In their recent trial, published in Vaccines, 100 percent of pigs immunised with the new vaccine survived a lethal dose of ASF virus. ASF causes…

Cattle and goats in Tanzania

Host defence genes may contribute to peste des petits ruminants susceptibility

Differences in the host immune response may explain why cattle are less susceptible to peste des petits ruminants (PPR) than goats, according to a collaborative research effort by scientists at The Pirbright Institute and the Tamil Nadu Veterinary and Animal Sciences…

Sheep being moved across the plains in Mongolia by nomadic herders

Pirbright calculates impact of foot-and-mouth disease control in Mongolia

Researchers at The Pirbright Institute have collaborated with State Central Veterinary Laboratories (SCVL) and the General Agency for Veterinary Services (GAVS) in Mongolia to assess the impact of foot-and-mouth disease (FMD) control methods employed during the 2017…