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Merged cells following co-expression of the SARS-CoV-2 spike glycoprotein and human ACE2 receptors.

SARS-CoV-2 has the potential to enter animal cells

Scientists at The Pirbright Institute have shown that severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), responsible for coronavirus disease (COVID-19), is able to enter cells using the receptors of multiple mammalian species. The broad host range of SARS-CoV-2…

Merged cells following co-expression of the SARS-CoV-2 spike glycoprotein and human ACE2 receptors.

SARS-CoV-2 has the potential to enter animal cells

Scientists at The Pirbright Institute have shown that severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), responsible for coronavirus disease (COVID-19), is able to enter cells using the receptors of multiple mammalian species. The broad host range of SARS-CoV-2…

Merged cells following co-expression of the SARS-CoV-2 spike glycoprotein and human ACE2 receptors.

SARS-CoV-2 has the potential to enter animal cells

Scientists at The Pirbright Institute have shown that severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), responsible for coronavirus disease (COVID-19), is able to enter cells using the receptors of multiple mammalian species. The broad host range of SARS-CoV-2…

Merged cells following co-expression of the SARS-CoV-2 spike glycoprotein and human ACE2 receptors.

SARS-CoV-2 has the potential to enter animal cells

Scientists at The Pirbright Institute have shown that severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), responsible for coronavirus disease (COVID-19), is able to enter cells using the receptors of multiple mammalian species. The broad host range of SARS-CoV-2…

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Diversity of transmission outcomes following co-infection of sheep with strains of bluetongue virus serotype 1 and 8

Bluetongue virus (BTV) causes an economically important disease, bluetongue (BT), in susceptible ruminants and is transmitted primarily by species of Culicoides biting midges (Diptera: Ceratopogonidae). Since 2006, northern Europe has experienced multiple incursions of BTV…

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Diversity of transmission outcomes following co-infection of sheep with strains of bluetongue virus serotype 1 and 8

Bluetongue virus (BTV) causes an economically important disease, bluetongue (BT), in susceptible ruminants and is transmitted primarily by species of Culicoides biting midges (Diptera: Ceratopogonidae). Since 2006, northern Europe has experienced multiple incursions of BTV…

default publication image

Diversity of transmission outcomes following co-infection of sheep with strains of bluetongue virus serotype 1 and 8

Bluetongue virus (BTV) causes an economically important disease, bluetongue (BT), in susceptible ruminants and is transmitted primarily by species of Culicoides biting midges (Diptera: Ceratopogonidae). Since 2006, northern Europe has experienced multiple incursions of BTV…

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Comparing the efficacy of formaldehyde with hydrogen peroxide fumigation on infectious bronchitis virus

Background: The recent reclassification of formaldehyde as a presumed carcinogen prompted the investigation into the comparative efficacy of hydrogen peroxide as a fumigant in microbiological safety cabinets. Introduction: The aim of the study was to quantify the biocidal…

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A unifying structural and functional model of the coronavirus replication organelle: tracking down RNA synthesis

Zoonotic coronavirus (CoV) infections, such as those responsible for the current severe acute respiratory syndrome-CoV 2 (SARS-CoV-2) pandemic, cause grave international public health concern. In infected cells, the CoV RNA-synthesizing machinery associates with modified…

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ATM-mediated DNA double-strand break response facilitated oncolytic Newcastle disease virus replication and promoted syncytium formation in tumor cells

Various viruses have evolved a plethora of strategies to manipulate DNA damage machinery and commandeer cells to maximize their own replication. On the contrary, host cells have also evolved to maintain cellular genomic stability and suppress carcinogenesis through…