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Taking science beyond the laboratory- helping researchers, farmers, and policy makers in Nigeria

Researchers at The Pirbright Institute together with the Royal Veterinary College in London have been working with scientists at the National Veterinary Research Institute (NVRI), farmers and policy makers in Nigeria to tackle the devastating effects of sheeppox and goatpox…

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Pirbright’s openness on animal research rewarded

The Pirbright Institute continues to hold the Leader in Openness award for 2022-2025. This has been awarded by Understanding Animal Research (UAR). This award recognises the Institute’s commitment to the UAR Concordat on Openness on Animal Research in the UK which has been…

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New ways of identifying chickens explored by Pirbright’s Animal Technicians

Animal Technicians at Pirbright have explored less invasive methods of identifying chickens in research environments. This could improve the welfare of poultry in research and still provide an effective method to identify individuals during an experiment. The team explored…

Timewise Power List 2022 award winners announced

Pirbright scientist, Dr Jane Edwards, announced as a winner of the 2022 Timewise Power List. This award recognises those who achieve phenomenal success while working flexibly or part time. Jane was one of just 25 winners after 13 judges deemed her story to be an inspiration…

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Diversity and abundance of tabanids in Northern Spain

Tabanids (Diptera: Tabanidae) are large haematophagous flies that cause both direct (by biting nuisance) and indirect (primarily by mechanical transmission of diseases) damage to host species. Research studies on this family have received little attention in some parts of…

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African swine fever virus and host response - transcriptome profiling of the Georgia 2007/1 strain and porcine macrophages

African swine fever virus (ASFV) has a major global economic impact. With a case fatality in domestic pigs approaching 100%, it currently presents the largest threat to animal farming. Although genomic differences between attenuated and highly virulent ASFV strains have been…

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Report of a new meq gene size: The first study on genetic characterization of Marek's disease viruses circulating in Iranian commercial layer and backyard chicken

In recent months, several outbreaks with clinical signs of MDV-1 were reported in Iranian parent and laying hen farms, in addition to backyard chickens. Several meq gene sequences from these outbreaks were amplified and molecularly characterised.The meq protein sequences…

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A novel strain of lumpy skin disease virus causes clinical disease in cattle in Hong Kong

Lumpy skin disease virus (LSDV) is an emerging poxviral pathogen of cattle that is currently spreading throughout Asia. The disease situation is of high importance for farmers and policy makers in Asia. In October 2020, feral cattle in Hong Kong developed multi-focal…

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A recombinant turkey herpesvirus expressing the F protein of Newcastle disease virus genotype XII generated by NHEJ-CRISPR/Cas9 and Cre-LoxP systems confers protection against genotype XII challenge in chickens

In this study, we developed a new recombinant virus rHVT-F using a Turkey herpesvirus (HVT) vector, expressing the fusion (F) protein of the genotype XII Newcastle disease virus (NDV) circulating in Peru. We evaluated the viral shedding and efficacy against the NDV genotype…

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CRISPR/Cas9 editing of duck enteritis virus genome for the construction of a recombinant vaccine vector expressing omph gene of Pasteurella multocida in two novel insertion sites

Duck enteritis virus (DEV) and Pasteurella multocida, the causative agent of duck plague and fowl cholera, are acute contagious diseases and leading causes of morbidity and mortality in duck. The NHEJ-CRISPR/Cas9-mediated gene editing strategy, accompanied with the Cre–Lox…