Research paper The molecular biology of nairoviruses, an emerging group of tick-borne arboviruses The nairoviruses are a rapidly emerging group of tick-borne bunyaviruses that includes pathogens of humans (Crimean-Congo hemorrhagic fever virus [CCHFV]) and livestock (Nairobi sheep disease virus [NSDV], also known as Ganjam virus), as well as a large number of viruses for… Read more
Basic page Non-vesicular disease diagnostic testing Testing for African horse sickness, African swine fever, bluetongue, Capripox (sheep pox, goat pox and lumpy skin disease), epizootic haemorrhagic disease, and peste des petits ruminants. Read more
Research paper The Nairovirus Nairobi sheep disease virus/Ganjam virus induces the translocation of protein disulphide isomerase-like oxidoreductases from the endoplasmic reticulum to the cell surface and the extracellular space Nairobi sheep disease virus (NSDV) of the genus Nairovirus causes a haemorrhagic gastroenteritis in sheep and goats with mortality up to 90%; the virus is found in East and Central Africa, and in India, where the virus is called Ganjam virus. NSDV is closely related to the… Read more
Research paper Aptamer-based biosensors for the rapid visual detection of flu viruses RNA aptamers showing affinity and specificity for different strains of human influenza virus were assembled onto gold nanoparticles that subsequently formed a gold nanoshell (AuNS) around the viral envelope. These shells could be visualised by transmission electron… Read more
Research paper Nucleotide variability at its limit? Insights into the number and evolutionary dynamics of the sex-determining specificities of the honey bee Apis mellifera Deciphering the evolutionary processes driving nucleotide variation in multiallelic genes is limited by the number of genetic systems in which such genes occur. The complementary sex determiner (csd) gene in the honey bee Apis mellifera is an informative example for studying… Read more
Research paper A thiazepino[4,5-a]benzimidazole derivative hampers the RNA replication of Eurasian serotypes of foot-and-mouth disease virus The stamping-out policy for the control of foot-and-mouth disease virus (FMDV) in countries that are free from FMD without vaccination has a dramatic socio-economic impact, huge animal welfare issues and may result in the loss of farm animal genetic resources. As an… Read more
Research paper Genetic elimination of field-cage populations of Mediterranean fruit flies The Mediterranean fruit fly (medfly, Ceratitis capitata Wiedemann) is a pest of over 300 fruits, vegetables and nuts. The sterile insect technique (SIT) is a control measure used to reduce the reproductive potential of populations through the mass release of sterilized male… Read more
Research paper The function of targeted host genes determines the oncogenicity of HBV integration in hepatocellular carcinoma Although hepatitis B virus (HBV) integration into the human genome has been considered as one of the major causative factors to hepatocarcinogenesis, the underlying mechanism(s) was still elusive. Here we investigate the essential difference(s) of HBV integration between HCC… Read more
Research paper Evolutionary genetics underlying the spread of peste des petits ruminants virus Peste des petits ruminants (PPR) constitutes one of the major hurdles to the improvement of small-ruminant production in countries where it is endemic, directly affecting the poor, the main keepers of those species. Despite the existence of highly effective vaccines for more… Read more
Research paper Correlation of cell surface marker expression with African swine fever virus infection The expression of surface markers on African swine fever virus (ASFV) infected cells was evaluated to assess their involvement in infection. Previous findings indicated CD163 expression was correlated with ASFV susceptibility. However, in this study the expression of porcine… Read more
