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Marek’s disease (MD), caused by Marek’s disease virus (MDV), is a commercially important neoplastic disease of poultry which is only controlled by mass vaccination. Importantly, vaccines that can provide sterile immunity and inhibit virus transmission are lacking; such that…

Rinderpest was one of the most devastating veterinary diseases affecting even-toed ungulates until it was eradicated globally in 2011. Caused by the rinderpest virus (RPV), at its height rinderpest was prevalent in many parts of Europe, Africa and Asia. An ancient disease…

Avian metapneumovirus (aMPV) is the type species of the genus Metapneumovirus in the subfamily Pneumovirinae within the family Paramyxoviridae. The genome encodes eight discrete transcription units, which are generally assumed to code for nine proteins. Genes are flanked by…

The Mediterranean olive tree (Olea europaea subsp. europaea) was one of the first trees to be domesticated and is currently of major agricultural importance in the Mediterranean region as the source of olive oil. The molecular bases underlying the phenotypic differences…

Newcastle disease (ND) is one of the most devastating poultry diseases and can affect a broad range of avian species. Being a good animal model virus, and with the availability of reverse genetics, the pathobiology of ND virus (NDV) has been well studied. However, despite…

Immune dysfunction can be either at the humoral or cellular levels and is mediated by a myriad of factors including virus-induced immunosuppression. Infectious bursal disease virus (IBDV) affects domesticated poultry and causing health problems mainly due to prolonged…

The recent super-exponential growth in the amount of sequencing data generated worldwide has put techniques for compressed storage into the focus. Most available solutions, however, are strictly tied to specific bioinformatics formats, sometimes inheriting from them…

Newcastle disease virus (NDV) is a prototype member of avian paramyxovirus serotype 1 (APMV-1), which causes severe and contagious disease in the commercial poultry and wild birds. Despite extensive vaccination programs and other control measures, the disease remains endemic…