Search | The Pirbright Institute

Filters

default publication image

Supplementation of Vitamin E protects chickens from Newcastle disease virus-mediated exacerbation of intestinal oxidative stress and tissue damage

Newcastle disease virus (NDV) causes a highly devastating and contagious disease in poultry, which is mainly attributed to extensive tissue damages in the digestive, respiratory and nervous systems. However, nature and dynamics of NDV-induced oxidative stresses in the…

At The Pirbright Institute Dr Mark Fife is committed to bee conservation

To bee, or not to bee? It’s not really a question for Dr Mark Fife, leader of the Genetics and Genomics group at The Pirbright Institute, who has installed two hives on site and whose honey bees (Apis mellifera) produced 42 pounds of honey in the first crop this summer…

Pirbright lead €5.6 million consortium to DEFEND against African swine fever and lumpy skin disease

African swine fever (ASF) and lumpy skin disease (LSD) represent an immediate and serious threat to the pig and cattle industries in Europe and eastern and central Asia. The need for a more collaborative approach to tackle these diseases has been recognised by the European…

nipah virus

Pirbright scientists are developing vaccine candidates for animal viruses that cause human disease

World Zoonoses Day on 6 July is dedicated to raising awareness and understanding of zoonoses – diseases that spread from animals to humans. Zoonoses are a focus of research at The Pirbright Institute, a national research centre that works to enhance the UK’s capability to…

Novel sampling method can detect foot-and-mouth disease in absence of clinical infection

Surveillance of livestock and their environment for the presence of FMDV is an important part of preventing outbreaks of foot-and-mouth disease (FMD), a disease which creates a socio-economic burden for the farming industry and smallholder or subsistence farmers alike…

Novel sampling method can detect foot-and-mouth disease in absence of clinical infection

Surveillance of livestock and their environment for the presence of FMDV is an important part of preventing outbreaks of foot-and-mouth disease (FMD), a disease which creates a socio-economic burden for the farming industry and smallholder or subsistence farmers alike…

default publication image

Development of a high-throughput ex-vivo burn wound model using porcine skin, and its application to evaluate new approaches to control wound infection

Biofilm formation in wounds is considered a major barrier to successful treatment, and has been associated with the transition of wounds to a chronic non-healing state. Here, we present a novel laboratory model of wound biofilm formation using ex-vivo porcine skin and a…

default publication image

Biological characterization of wild-bird-origin avian avulavirus 1 and efficacy of currently applied vaccines against potential infection in commercial poultry

Newcastle disease virus (NDV), the type member of the species Avian avulavirus 1 (formerly known as avian paramyxovirus serotype 1), causes a highly contagious and economically important disease in a myriad of avian species around the globe. While extensive vaccination…

default publication image

Nomenclature for the KIR of non-human species

The increasing number of Killer Immunoglobulin-like Receptor (KIR) sequences available for non-human primate species and cattle has prompted development of a centralized database, guidelines for a standardized nomenclature, and minimum requirements for database submission…

default publication image

The unique evolution of the pig LRC, a single KIR but expansion of LILR and a novel Ig receptor family

The leukocyte receptor complex (LRC) encodes numerous immunoglobulin (Ig)-like receptors involved in innate immunity. These include the killer-cell Ig-like receptors (KIR) and the leukocyte Ig-like receptors (LILR) which can be polymorphic and vary greatly in number between…