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H7N9 flu mutation identified that allows immune system escape

Scientists at The Pirbright Institute have identified a key mutation in the H7N9 avian influenza virus which could allow it to escape immune system defences, reducing the effectiveness of vaccines. The research, published in the Journal of Virology, demonstrated that small…

DNA cell

Pirbright scientists use ground-breaking techniques to identify how a ruminant virus can adapt to infect human cells

Scientists from The Pirbright Institute have used a ground-breaking approach to identify that a morbillivirus that causes disease in small ruminants such as sheep and goats, known as peste des petits ruminants (a close relative of measles virus – the human morbillivirus)…

Ada Lovelace Day: Celebrating women in science

To celebrate Ada Lovelace Day, today 9 October, we asked everyone at Pirbright to nominate their female STEM role model with a short explanation on why they were nominating them. Miriam Windsor, Research Services Capability Leader, nominated Pirbright’s Dr Geraldine Taylor…

Ada Lovelace Day: Celebrating women in science

To celebrate Ada Lovelace Day, today 9 October, we asked everyone at Pirbright to nominate their female STEM role model with a short explanation on why they were nominating them. Miriam Windsor, Research Services Capability Leader, nominated Pirbright’s Dr Geraldine Taylor…

Pirbright scientists produce lab technique which reduces need for experimental chickens

Scientists from The Pirbright Institute have created a laboratory procedure which allows the response of chicken immune cells to infectious bursal disease virus (IBDV) to be studied without infecting live chickens. IBDV, also known as Gumboro disease, can result in…

foot-and-mouth disease spread from the indian subcontinent reconstructed through genetic analysis

Pirbright collaboration maps foot-and-mouth disease escape from Indian subcontinent

Scientists from The Pirbright Institute have used state-of-the-art approaches to monitor foot-and-mouth disease (FMD) outbreaks that have recently radiated out from the Indian subcontinent. The seven different types of FMD virus (called serotypes) can be split further into…

Pirbright reference lab detects bluetongue in two imported cattle

Bluetongue virus type 8 was successfully identified in two imported cattle recently by the National Reference Laboratory for Bluetongue virus, part of the Non-Vesicular Disease Reference Laboratory Group’s diagnostic facilities here at Pirbright, and the Animal and Plant…

white mouse in tube with red eyes

Engineering ‘Fab’ new ways of reducing animal use in foot-and-mouth disease diagnostics

A novel foot-and-mouth disease (FMD) diagnostic reagent has been developed by scientists at The Pirbright Institute. This has the potential to be used in FMD diagnostic tests, and will be significantly quicker to produce when compared to existing test reagents due to a…

white mouse in tube with red eyes

Engineering ‘Fab’ new ways of reducing animal use in foot-and-mouth disease diagnostics

A novel foot-and-mouth disease (FMD) diagnostic reagent has been developed by scientists at The Pirbright Institute. This has the potential to be used in FMD diagnostic tests, and will be significantly quicker to produce when compared to existing test reagents due to a…

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Structure-guided identification of a non-human morbillivirus with zoonotic potential

Morbilliviruses infect a broad range of mammalian hosts including ruminants, carnivores and humans. The recent eradication of rinderpest virus (RPV), as well as active campaigns for the human-specific measles virus (MeV), have raised significant concerns that the remaining…