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Animal care

Rigorous animal care and staff training protocols ensure the highest standards of health, welfare, and competence for all animals.

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Legislation and licencing

The Pirbright Institute adheres to rigorous legislation.

Pirbright tackle peste des petits ruminants from all fronts

Scientists at The Pirbright Institute provide critical services for the peste des petits ruminants (PPR) eradication campaign. Outbreaks of PPR, a viral disease that mainly infects goats and sheep, occur mostly across Africa, Middle East and India, which currently cost…

Pirbright scientists show re-emerged bluetongue strain still poses a threat

Scientists at The Pirbright Institute have shown that the strain of bluetongue virus (BTV) currently circulating in France poses a threat to susceptible animals in Europe, despite causing less clinical disease than the original BTV-8 strain responsible for the first UK…

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Higher levels of B-cell mutation in the early germinal centres of an inefficient secondary antibody response to a variant Influenza Haemagglutinin

Designing improved vaccines against mutable viruses such as Dengue and Influenza would be helped by a better understanding of how the B-cell memory compartment responds to variant antigens. Towards this we have recently shown after secondary immunization of mice with a…

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Avian influenza viruses at the wild-domestic bird interface in Egypt

Wild birds of the orders Anseriformes (mainly ducks, geese and swans) and Charadriiformes (mainly gulls, terns and waders) constitute the natural reservoir for low pathogenic avian influenza (LPAI) viruses. In Egypt, highly pathogenic avian influenza (HPAI) H5N1 and LPAI…

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Opportunities for enhanced surveillance of foot-and-mouth disease in endemic settings using milk samples

Under-reporting of foot-and-mouth disease (FMD) masks the true prevalence in parts of the world where the disease is endemic. Laboratory testing for the detection of FMD virus (FMDV) is usually reliant upon the collection of vesicular epithelium and fluid samples that can…

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OIE reference laboratories for PPR provide support to the PPR Global Eradication Programme

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Vaccine development for Nipah virus infection in pigs

Nipah virus (NiV) causes a severe and often fatal neurological disease in humans. Whilst fruit bats are considered the natural reservoir, NiV also infects pigs and may cause an unapparent or mild disease. Direct pig-to-human transmission was responsible for the first and…

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T and B cell immune responses to influenza viruses in pigs

Influenza viruses are an ongoing threat to humans and are endemic in pigs, causing considerable economic losses to farmers. Pigs are also a source of new viruses potentially capable of initiating human pandemics. Many tools including monoclonal antibodies, recombinant…