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Pirbright workshop explores avian flu control

A workshop hosted by The Pirbright Institute convened world-leading experts to explore ways of reducing the impact of bird flu on livestock, poultry production and human health. Hosted at the Institute’s site in Surrey, the two-day event brought together international…

Three sheep in a field

Study confirms the clinical impact of a BTV-3 outbreak on the UK sheep population

A new study highlights the potentially serious consequences of bluetongue virus serotype 3 (BTV-3) on the UK sheep population. This BTV-3 strain emerged in Northern Europe in September 2023 and has since been reported in 16 countries across the continent, causing outbreaks…

Three sheep in a field

Study confirms the clinical impact of a BTV-3 outbreak on the UK sheep population

A new study highlights the potentially serious consequences of bluetongue virus serotype 3 (BTV-3) on the UK sheep population. This BTV-3 strain emerged in Northern Europe in September 2023 and has since been reported in 16 countries across the continent, causing outbreaks…

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Evaluation of commercial quadrivalent foot-and-mouth disease vaccines against east African virus strains reveals limited immunogenicity and duration of protection

Foot-and-mouth disease virus (FMDV) causes a contagious disease (FMD) in cloven-hoofed animals. For FMD-endemic countries, vaccination is critical for controlling disease but is rarely monitored, despite substantial funds spent on vaccine purchases. We evaluated antibody…

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High pathogenicity avian influenza H5N5: the next threat?

Linda, Alison and Louise. Linda is stood behind Alison and Louise with gold balloons 4 and 0 while Alison and Louise are sat. Alison on the left holds a gold 2 balloon while Louise holds a gold 5 balloon.

Three dedicated staff celebrate Long Service Awards

Three dedicated colleagues who have worked at The Pirbright Institute for a combined total of 90 years are celebrating Long Service Awards. Group leader Dr Linda Dixon has served 40 years, whilst researcher Dr Alison Burman and animal services specialist Louise Stevenson are…

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Activation of the mitochondrial unfolded protein response regulates the dynamic formation of stress granules

To rapidly adapt to harmful changes to their environment, cells activate the integrated stress response (ISR). This results in an adaptive transcriptional and translational rewiring, and the formation of biomolecular condensates named stress granules (SGs), to resolve stress…

Artist impression of CVIM building

CVIM to accelerate global vaccine development

The Pirbright Institute is partnering with Scitech, a leading specialist in pharmaceutical design, engineering, construction and qualification, to build and deliver a new Centre for Veterinary Vaccine Innovation and Manufacturing (CVIM). CVIM’s mission is to fulfil an unmet…

Aerial shot of The Brooksby Building surrounded by woodland and The Pirbright Institute site

Major new facility supports pandemic preparedness

A major new high-biological containment science facility, to be named The Brooksby Building, has been completed by The Pirbright Institute. Pirbright is the UK’s world-leading centre of excellence in research and surveillance of viral diseases of livestock, and viruses that…

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Genetic coping mechanisms observed in Leishmania tropica, from the Middle East region, enhance the survival of the parasite after drug exposure

Introduction: Cutaneous leishmaniasis caused by L. tropica is common in the Middle East and treatment failure and drug resistance are known to occur. Several genetic mechanisms: aneuploidy, recombination and loss of heterozygosity, single nucleotide polymorphism (SNP)…