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Eight mpox cells under the microscope and coloured bright blue

Pirbright to join efforts in mpox research as part of new consortium

The Pirbright Institute is taking a lead role in a new mpox consortium. The group will work together to develop better diagnostic tests, identify potential therapies and study vaccine effectiveness and the virus’ spread. The mpox Consortium has received £2million investment…

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Simultaneous protective immune responses of ducks against duck plague and fowl cholera by recombinant duck enteritis virus vector expressing Pasteurella multocida OmpH gene

Duck enteritis virus and Pasteurella multocida are major duck pathogens that induce duck plague and fowl cholera, respectively, in ducks and other waterfowl populations, leading to high levels of morbidity and mortality. Immunization with live attenuated DEV vaccine…

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Duck CD8(+) T cell response to H5N1 highly pathogenic avian influenza virus infection in vivo and in vitro

Domestic ducks are the important host for H5N1 highly pathogenic avian influenza virus (HPAIV) infection and epidemiology, but little is known about the duck T cell response to H5N1 AIV infection. In infection experiments of mallard ducks, we detected significantly increased…

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A temperature-sensitive recombinant of avian coronavirus infectious bronchitis virus provides complete protection against homologous challenge

Avian coronavirus infectious bronchitis virus (IBV) is the etiological agent of infectious bronchitis, an acute highly contagious economically relevant respiratory disease of poultry. Vaccination is used to control IBV infections, with live-attenuated vaccines generated via…

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Establishing an in vitro system to assess how specific antibodies drive the evolution of foot-and-mouth disease virus

Viruses can evolve to respond to immune pressures conferred by specific antibodies generated after vaccination and/or infection. In this study, an in vitro system was developed to investigate the impact of serum-neutralising antibodies upon the evolution of a foot-and-mouth…

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Establishing an in vitro system to assess how specific antibodies drive the evolution of foot-and-mouth disease virus

Viruses can evolve to respond to immune pressures conferred by specific antibodies generated after vaccination and/or infection. In this study, an in vitro system was developed to investigate the impact of serum-neutralising antibodies upon the evolution of a foot-and-mouth…

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Establishing an in vitro system to assess how specific antibodies drive the evolution of foot-and-mouth disease virus

Viruses can evolve to respond to immune pressures conferred by specific antibodies generated after vaccination and/or infection. In this study, an in vitro system was developed to investigate the impact of serum-neutralising antibodies upon the evolution of a foot-and-mouth…

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Infravec2 guidelines for the design and operation of containment level 2 and 3 insectaries in Europe

With the current expansion of vector-based research and an increasing number of facilities rearing arthropod vectors and infecting them with pathogens, common measures for containment of arthropods as well as manipulation of pathogens are becoming essential for the design…

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OMIP-085: Cattle B-cell phenotyping by an 8-color panel

This 8-color panel has been optimized to distinguish between functionally distinct subsets of cattle B cells in both fresh and cryopreserved peripheral blood mononuclear cells (PBMCs). Existing characterized antibodies against cell surface molecules (immunoglobulin light…

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OMIP-085: Cattle B-cell phenotyping by an 8-color panel

This 8-color panel has been optimized to distinguish between functionally distinct subsets of cattle B cells in both fresh and cryopreserved peripheral blood mononuclear cells (PBMCs). Existing characterized antibodies against cell surface molecules (immunoglobulin light…