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Blue coronavirus particles

Research project

Probing the molecular basis of translation replication switching in pathogenic RNA viruses

Understanding +ssRNA virus genome regulation for improved outbreak control.

A digitally colorized transmission electron microscopic (TEM) image of Zika virus. Virus particles are coloured red, the rest of the cell image is purple.

Research project

How does Musashi 1 enhance Zika virus replication?

Determining role of RNA binding protein Musashi-1 in enhancing Zika virus replication.

Two brown roosters on grass by a fence

Avian Genetics

Exploring chicken immunogenetics and viral evolution to enhance poultry resilience and tackle emerging threats.

Bioinformatics, Sequencing & Proteomics

The Bioinformatics, Sequencing & Proteomics research group focuses on developing methods to generate, analyse, and interpret large, complex biological datasets from advanced sequencing techniques to gain a deeper understanding of biological processes at a highly detailed…

Group of seven white Pekin ducks walking in a line on green grass

Avian Virology

Understanding and predicting avian influenza evolution to inform disease prevention.

Nipah virus particle

Research project

DNA-launched Nipah virus vaccines and therapeutics

Developing DNA vaccines and therapies to tackle Nipah virus outbreaks and prevent future pandemics.

Cows and calf in field against blue sky and cloud

Immunogenetics

Investigating genetic diversity in livestock to enhance immune responses and improve disease resistance.

Viral Immunology

Developing novel foot-and-mouth disease vaccines by studying immune responses and virus persistence in livestock.

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Immunisation with bacterial expressed VP2 and VP5 of bluetongue virus (BTV) protect ?/? interferon-receptor knock-out (IFNAR?/?) mice from homologous lethal challenge

BTV-4 structural proteins VP2 (as two domains: VP2D1 and VP2D2), VP5 (lacking the first 100 amino acids: VP5?1100) and full-length VP7, expressed in bacteria as soluble glutathione S-transferase (GST) fusion-proteins, were used to immunise Balb/c and ?/? interferon receptor…

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Proteome-wide screening of the European porcine reproductive and respiratory syndrome virus reveals a broad range of T cell antigen reactivity

The porcine reproductive and respiratory syndrome virus (PRRSV) is a rapidly evolving and diversifying pathogen necessitating the development of improved vaccines. Immunity to PRRSV is not well understood although there are data suggesting that virus-specific T cell IFN…