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A standardized method to study immune responses using porcine whole blood

Background: Peripheral blood mononuclear cells (PBMCs) are commonly used to assess in vitro immune responses. However, PBMC isolation is a time-consuming procedure, introduces technical variability, and requires a relatively large volume of blood. By contrast, whole blood…

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An Infectious Bursal Disease Virus (IBDV) Reverse Genetics Rescue System and Neutralization Assay in Chicken B Cells

Infectious bursal disease virus (IBDV) is a major threat to the productivity of the poultry industry due to morbidity, mortality, and immunosuppression that exacerbates secondary infections and reduces the efficacy of vaccination programs. Field strains of IBDV have a…

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An Infectious Bursal Disease Virus (IBDV) Reverse Genetics Rescue System and Neutralization Assay in Chicken B Cells

Infectious bursal disease virus (IBDV) is a major threat to the productivity of the poultry industry due to morbidity, mortality, and immunosuppression that exacerbates secondary infections and reduces the efficacy of vaccination programs. Field strains of IBDV have a…

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Urban forest soils harbour distinct and more diverse communities of bacteria and fungi compared to less disturbed forest soils

Anthropogenic changes to land use drive concomitant changes in biodiversity, including that of the soil microbiota. However, it is not clear how increasing intensity of human disturbance is reflected in the soil microbial communities. To address this issue, we used amplicon…

Professor Bryan Charleston smiling in grey suit with white shirt

Professor Bryan Charleston elected as Fellow of the Royal Society

Professor Bryan Charleston, Director and CEO of The Pirbright Institute has been elected a Fellow of the Royal Society. Internationally renowned, Professor Charleston is an expert in host-pathogen interactions related to major viral diseases that affect livestock. His…

Three young visitors engaging with a screen. One is smiling and another is inquisitive

Pirbright showcases the best in science and community with open-door event

At the beginning of April, The Pirbright Institute welcomed over 800 people on site for two days of discovery, interaction and celebration. The Institute held two Celebration Days which provided a unique opportunity for staff, stakeholders, and members of the public to learn…

Heard of African buffalo in long grass with one looking directly at the camera

New UK Centre for Veterinary Vaccine Innovation and Manufacturing set to improve global animal health

A joint initiative between the UKRI Biotechnology and Biological Sciences Research Council (BBSRC), the Foreign, Commonwealth and Development Office (FCDO) and the Bill & Melinda Gates Foundation will see the creation of a new centre at The Pirbright Institute designed to…

The Pirbright Institute Modern Slavery and Human Trafficking Statement

The Pirbright Institute Modern Slavery & Human Trafficking Statement for 2025-2026 1. CONTEXT This Modern Slavery and Human Trafficking Statement relates to actions and activities for the financial year 2025-2026. The statement sets down The Pirbright Institute’s commitment…

Biological safety cabinet, lights on, next to two microscopes in a Pirbright laboratory

Biological safety cabinets - maintenance and validation: Instructor-led

Learn about how biological safety cabinets, how they work and how to maintain and validate.

Melanie Welham and Bryan Charleston stood either side of an easel stand which holds a brass plaque

Professor Melanie Welham officially opens The Biggs Avian Research Building at Pirbright

Professor Melanie Welham, Executive Chair of the Biotechnology and Biological Sciences Research Council (BBSRC), part of UK Research and Innovation (UKRI), officially opened The Biggs Avian Research Building today (23 February 2023) at The Pirbright Institute in Surrey. The…