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Research paper

Selection of variant viruses during replication and transmission of H7N1 viruses in chickens and turkeys

The influence of different glycosylation patterns of the haemagglutinin glycoprotein of H7N1 avian influenza viruses on virus replication in vivo was examined. Experimental infection of chickens and turkeys was carried out with H7N1 avian influenza viruses with alternative…
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Research paper

Evidence of seroconversion to SBV in camelids (Letter)

At the Royal Veterinary College (RVC), we are conducting a longitudinal serosurveillance of the livestock (about 150 cattle, 1250 sheep and 10 alpacas) on our farm for evidence of Schmallenberg virus (SBV) infection. There have already been three proven cases of SBV in our…
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Research paper

The importance of FMDV localisation in lymphoid tissue

Foot-and-mouth disease virus, a highly contagious pathogen that can cause lameness, low weight and decreased milk production, is a scourge of agricultural livestock around the world. Although the acute phase of infection is rarely fatal, infection may persist in animals that…
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Research paper

Foot-and-mouth disease virus serotypes detected in Tanzania from 2003 to 2010: conjectured status and future prospects

This study was conducted to investigate the presence of foot-and-mouth disease virus (FMDV) in different geographic locations of Tanzania. Epithelial tissues and fluids (n = 364) were collected from cattle exhibiting oral and foot vesicular lesions suggestive of FMD and…
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Research paper

New technologies to diagnose and monitor infectious diseases of livestock: Challenges for sub-Saharan Africa

Using foot-and-mouth disease (FMD) as an example, this review describes new tools that can be used to detect and characterise livestock diseases. In recent years, molecular tests that can detect and characterise pathogens in a diverse range of sample types have…
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Research paper

Southeast Asian foot-and-mouth disease viruses in Eastern Asia

Foot-and-mouth disease (FMD) outbreaks recently affected 2 countries (Japan and South Korea) in eastern Asia that were free of FMD without vaccination. Analysis of viral protein 1 nucleotide sequences indicated that FMD serotype A and 0 viruses that caused these outbreaks…
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Research paper

Field application of a recombinant protein-based ELISA during the 2010 outbreak of foot-and-mouth disease type A in South Korea

A recombinant protein-based enzyme-linked immunosorbent assay (RP ELISA) exists for the detection of antibodies to foot-and-mouth disease virus (FMDV) type A. In this study, the efficacy of the RP ELISA was compared to that of other current tests by examining sera collected…
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Research paper

Female-specific flightless (fsRIDL) phenotype for control of Aedes albopictus

The Asian Tiger mosquito, Aedes albopictus, is a highly invasive species which took advantage of human activity to spread from South-East Asia to Africa, North and South America, and Europe in the past forty years. Beyond the annoying biting nuisance, this mosquito is also a…
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Research paper

Open field release of genetically engineered sterile male Aedes aegypti in Malaysia

Background: Dengue is the most important mosquito-borne viral disease. In the absence of specific drugs or vaccines, control focuses on suppressing the principal mosquito vector, Aedes aegypti, yet current methods have not proven adequate to control the disease. New methods…
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Research paper

A defined intestinal colonization microbiota for gnotobiotic pigs

Maximising the ability of piglets to survive exposure to pathogens is essential to reduce early piglet mortality, an important factor in efficient commercial pig production. Mortality rates can be influenced by many factors, including early colonization by microbial…
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