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Newcastle disease virus

Newcastle disease (ND) is one of the most devastating poultry diseases and can affect a broad range of avian species. Being a good animal model virus, and with the availability of reverse genetics, the pathobiology of ND virus (NDV) has been well studied. However, despite…

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Interaction of infectious bursal disease virus with the immune system of poultry

Immune dysfunction can be either at the humoral or cellular levels and is mediated by a myriad of factors including virus-induced immunosuppression. Infectious bursal disease virus (IBDV) affects domesticated poultry and causing health problems mainly due to prolonged…

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CARGO: effective format-free compressed storage of genomic information

The recent super-exponential growth in the amount of sequencing data generated worldwide has put techniques for compressed storage into the focus. Most available solutions, however, are strictly tied to specific bioinformatics formats, sometimes inheriting from them…

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Detection of inter-lineage natural recombination in avian paramyxovirus serotype 1 using simplified deep sequencing platform

Newcastle disease virus (NDV) is a prototype member of avian paramyxovirus serotype 1 (APMV-1), which causes severe and contagious disease in the commercial poultry and wild birds. Despite extensive vaccination programs and other control measures, the disease remains endemic…

HRH The Princess Royal officially opens the BBSRC National Vaccinology Centre

HRH The Princess Royal officially opened the BBSRC National Vaccinology Centre: The Jenner Building today (24 March, 2017) – a world leading vaccine development facility, located at The Pirbright Institute in Surrey. The BBSRC National Vaccinology Centre accommodates 100…

Scientists join forces to halt the spread of African swine fever in Europe

Leading researchers from The Pirbright Institute have joined with other European scientists to share knowledge and expertise as part of an international collaboration to prevent the spread of African swine fever (ASF). The Institute recently hosted an international workshop…

Egg protein may hold the key to controlling the spread of bluetongue

A protein found in egg, could be used to help control the spread of the devastating livestock disease bluetongue (BT), say scientists from The Pirbright Institute. Bluetongue affects livestock including sheep (which are most severely affected), cattle and goats along with…

Expertise and facilities at Pirbright to help new EU consortium fight insect-borne diseases

The Pirbright Institute is to play a key role in a new international project funded by the European Commission, to fight the mosquito-transmitted diseases now threatening Europe. The Infravec2 Project is an international consortium of 24 partner institutions coordinated by…

Pirbright PhD student wins `Young Innovator of the Year`

A student studying for his PhD at The Pirbright Institute was named Young Innovator of the Year at the Guildford Innovation Awards 2017 on 22 February 2017. Tom Whitehead won the award for his research on egg anti-viral proteins which could lead to a major step forward in…

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Molecular evolution and emergence of H5N6 avian influenza virus in central China

H5N6 avian influenza virus (AIV) has posed a potential threat to public health since its emergence in China in 2013. To understand the evolution and emergence of H5N6 AIV in the avian population, we performed molecular surveillance of live poultry markets (LPMs) in Wugang…