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Antigenic characterization of highly pathogenic avian influenza A(H5N1) viruses with chicken and ferret antisera reveals clade-dependent variation in hemagglutination inhibition profiles

Highly pathogenic avian influenza (HPAI) A(H5N1) viruses pose a significant economic burden to the poultry industry worldwide and have pandemic potential. Poultry vaccination against HPAI A(H5N1) viruses has been an important component of HPAI control measures and has been…

cold virus

Breakthrough could make the common cold not so common

Researchers at The Pirbright Institute have helped in the development of a new molecule to treat a range of viruses including the common cold. In addition to the days of work lost due to illness, the common cold can cause complications in respiratory illnesses such as asthma…

National Insect week swat or swipe right

Swat or swipe-right? Insect sex lives revealed

Dr Simon Carpenter, Head of the Entomology group at Pirbright, swipes right on some stars of the insect dating scene for National Insect Week. The weird and wonderful sex lives of our chitinous cousins have long held a fascination with both the public and entomologists. A…

nipah virus

Nipah virus

Nipah virus (NiV) is an emerging zoonotic disease transmitted by fruit bats, with pigs serving as amplifying hosts that facilitate transmission to humans.

nipah virus

Nipah virus

Nipah virus (NiV) is an emerging zoonotic disease transmitted by fruit bats, with pigs serving as amplifying hosts that facilitate transmission to humans.

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Foot-and-mouth disease in the Middle East caused by an A/ASIA/G-VII virus lineage, 2015-2016

Phylogenetic analyses of foot-and-mouth disease type A viruses in the Middle East during 2015-2016 identified viruses belonging to the A/ASIA/G-VII lineage, which originated in the Indian subcontinent. Changes in a critical antigenic site within capsid viral protein 1…

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Molecular detection, isolation and characterization of peste-des-petits ruminants virus from goat milk from outbreaks in Bangladesh and its implication for eradication strategy

Peste-des-petits ruminants (PPR) is a highly contagious transboundary viral disease of small ruminants, which is endemic in much of Africa, the Middle East and Asia. In South Asia, PPR is of significant concern to the Indian subcontinent including Bangladesh as more than 30%…

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Gallid herpesvirus 3 SB-1 strain as a recombinant viral vector for poultry vaccination

Live herpesvirus-vectored vaccines are widely used in veterinary medicine to protect against many infectious diseases. In poultry, three strains of herpesvirus vaccines are used against Marek's disease (MD). However, of these, only the herpesvirus of turkeys (HVT) has been…

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Reproducibility and relevance in insect-arbovirus infection studies

Experimental infections of insects with arboviruses are performed to achieve a variety of objectives but principally to draw inferences about the potential role of field populations in transmission or to explore the molecular basis of vectorpathogen interactions. The design…

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Application of CRISPR/Cas9 gene editing system on MDV-1 genome for the study of gene function

Marek's disease virus (MDV) is a member of alphaherpesviruses associated with Marek's disease, a highly contagious neoplastic disease in chickens. Complete sequencing of the viral genome and recombineering techniques using infectious bacterial artificial chromosome (BAC)…