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Combatting the looming threat of bluetongue

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Crystal structure of African swine fever virus A179L with the autophagy regulator Beclin

Subversion of programmed cell death-based host defence systems is a prominent feature of infections by large DNA viruses. African swine fever virus (ASFV) is a large DNA virus and sole member of the Asfarviridae family that harbours the B-cell lymphoma 2 or Bcl-2 homolog…

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Crystal structure of African swine fever virus A179L with the autophagy regulator Beclin

Subversion of programmed cell death-based host defence systems is a prominent feature of infections by large DNA viruses. African swine fever virus (ASFV) is a large DNA virus and sole member of the Asfarviridae family that harbours the B-cell lymphoma 2 or Bcl-2 homolog…

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Bead-based multiplex assay for the simultaneous detection of antibodies to African swine fever virus and classical swine fever virus

African swine fever (ASF) and Classical swine fever (CSF) are both highly contagious diseases of domestic pigs and wild boar. In the last years, several cases of both diseases have been reported in the Caucasus, Russian Federation and Eastern Europe. Thus, the probability of…

Pirbright launches The Immunological Toolbox website

Scientists from The Pirbright Institute and The Roslin Institute have launched The Immunological Toolbox, a website that provides a platform for veterinary researchers to find resources and collaborate. The Toolbox aims to remove barriers to veterinary vaccine development by…

Vaccine being drawn from a vile

Pirbright partners with ECO Animal Health to combat poultry diseases

The Pirbright Institute has entered into a worldwide exclusive partnership with ECO Animal Health Ltd (ECO), a wholly owned subsidiary of ECO Animal Health Group plc, on two new projects to combat significant diseases of poultry. The first project, led by Professor Venugopal…

Vaccine being drawn from a vile

Pirbright partners with ECO Animal Health to combat poultry diseases

The Pirbright Institute has entered into a worldwide exclusive partnership with ECO Animal Health Ltd (ECO), a wholly owned subsidiary of ECO Animal Health Group plc, on two new projects to combat significant diseases of poultry. The first project, led by Professor Venugopal…

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Herpesvirus of turkeys (Meleagridis herpesvirus 1) encodes a functional microRNA-221 homolog with high sequence conservation

Herpesviruses account for most of the known virus-encoded miRNAs. Herpesvirus of turkey (HVT), a non-pathogenic avian herpesvirus used as an avian vaccine and viral vector, encodes 28 mature miRNAs. This included HVT-miR-H14-3p that showed almost identical sequence to gga…

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Poultry trading behaviours in Vietnamese live bird markets as risk factors for avian influenza infection in chickens

Vietnamese poultry are host to co-circulating subtypes of avian influenza viruses, including H5N1 and H9N2, which pose a great risk to poultry productivity and to human health. AIVs circulate throughout the poultry trade network in Vietnam, with live bird markets being an…

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MiR-125b suppression inhibits apoptosis and negatively regulates Sema4D in avian leukosis virus-transformed cells

Subgroup J avian leukosis virus (ALV-J), an oncogenic retrovirus, causes hemangiomas and myeloid tumors in chickens. We previously showed that miR-125b is down-regulated in ALV-J-induced tumors. This study aimed to investigate the possible role of miR-125b in ALV-J-mediated…