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Peste des petits ruminants at the wildlife–livestock interface in the Northern Albertine Rift and Nile Basin, East Africa

In the recent past, peste des petits ruminants (PPR) emerged in East Africa causing outbreaks in small livestock across different countries, with evidences of spillover to wildlife. In order to understand better PPR at the wildlife–livestock interface, we investigated…

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Culicoides species composition and molecular identification of host blood meals at two zoos in the UK

Culicoides biting midges are biological vectors of arboviruses including bluetongue virus (BTV), Schmallenberg virus (SBV) and African horse sickness virus (AHSV). Zoos are home to a wide range of ‘at risk’ exotic and native species of animals. These animals have a high…

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Culicoides species composition and molecular identification of host blood meals at two zoos in the UK

Culicoides biting midges are biological vectors of arboviruses including bluetongue virus (BTV), Schmallenberg virus (SBV) and African horse sickness virus (AHSV). Zoos are home to a wide range of ‘at risk’ exotic and native species of animals. These animals have a high…

default publication image

Culicoides species composition and molecular identification of host blood meals at two zoos in the UK

Culicoides biting midges are biological vectors of arboviruses including bluetongue virus (BTV), Schmallenberg virus (SBV) and African horse sickness virus (AHSV). Zoos are home to a wide range of ‘at risk’ exotic and native species of animals. These animals have a high…

default publication image

Culicoides species composition and molecular identification of host blood meals at two zoos in the UK

Culicoides biting midges are biological vectors of arboviruses including bluetongue virus (BTV), Schmallenberg virus (SBV) and African horse sickness virus (AHSV). Zoos are home to a wide range of ‘at risk’ exotic and native species of animals. These animals have a high…

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Population-level multiplexing, a promising strategy to manage the evolution of resistance against gene drives targeting a neutral locus

CRISPR-based gene drives bias inheritance in their favour by inducing double-stranded breaks (DSBs) at wild-type homologous loci and using the drive transgene as a repair template – converting drive heterozygotes into homozygotes. Recent studies have shown that alternate end…

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Age of first infection across a range of parasite taxa in a wild mammalian population

Newborn mammals have an immature immune system that cannot sufficiently protect them against infectious diseases. However, variation in the effectiveness of maternal immunity against different parasites may couple with temporal trends in parasite exposure to influence…

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The African swine fever virus transcriptome

African Swine Fever Virus (ASFV) causes haemorrhagic fever in domestic pigs, presenting the biggest global threat to animal farming in recorded history. Despite its importance, little is known about the mechanisms and regulation of ASFV transcription. Using RNA sequencing…

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Foot-and-mouth disease virus: prospects for using knowledge of virus biology to improve control of this continuing global threat

Understanding of the biology of foot-and-mouth disease virus (FMDV) has grown considerably since the nucleotide sequence of the viral RNA was determined. The ability to manipulate the intact genome and also to express specific parts of the genome individually has enabled…

Nipah virus particle

Pirbright shows new Nipah vaccines create ‘impressive’ immune response

Scientists at The Pirbright Institute have shown that two new potential vaccines against Nipah virus developed by the University of Parma generate a strong immune response in pigs. These promising results suggest the vaccines could protect pigs against Nipah virus infection…