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Characterisation of peste des petits ruminants disease in pastoralist small ruminant flocks in Ngorongoro District of northern Tanzania: variation in clinical syndromes and local diseases names, and bluetongue virus co-infection

Peste des petits ruminants (PPR) disease was first confirmed in Tanzania in 2008 in sheep and goats in Ngorongoro District, northern Tanzania, and is now endemic in this area. This study aimed to characterise PPR disease in pastoralist small ruminant flocks in Ngorongoro…

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Two lineages of KLRA with contrasting transcription patterns have been conserved at a single locus during ruminant speciation

Cattle possess the most diverse repertoire of NK cell receptor genes among all mammals studied to date. Killer cell receptor genes encoded within the NK complex and killer cell Ig-like receptor genes encoded within the leukocyte receptor complex have both been expanded and…

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Two lineages of KLRA with contrasting transcription patterns have been conserved at a single locus during ruminant speciation

Cattle possess the most diverse repertoire of NK cell receptor genes among all mammals studied to date. Killer cell receptor genes encoded within the NK complex and killer cell Ig-like receptor genes encoded within the leukocyte receptor complex have both been expanded and…

Close up of two Culicoides biting midges on human skin

Monitoring midge habits in zoos could hold important clues for disease outbreaks

The first study to confirm the feeding habits of midges on exotic animals in UK zoos has been published in Parasites and Vectors and could hold important clues to prevent disease outbreaks in Northern Europe. A team of researchers from The Pirbright Institute, the Zoological…

Close up of two Culicoides biting midges on human skin

Monitoring midge habits in zoos could hold important clues for disease outbreaks

The first study to confirm the feeding habits of midges on exotic animals in UK zoos has been published in Parasites and Vectors and could hold important clues to prevent disease outbreaks in Northern Europe. A team of researchers from The Pirbright Institute, the Zoological…

Pirbright supports UK’s effort to ramp up diagnostic testing for COVID-19

The Pirbright Institute, which is home to several World Reference Laboratories for viral diseases of livestock, is using its equipment and expertise in diagnostics and disease surveillance to support COVID-19 testing in the UK. The Institute is helping in three key areas…

Pirbright supports UK’s effort to ramp up diagnostic testing for COVID-19

The Pirbright Institute, which is home to several World Reference Laboratories for viral diseases of livestock, is using its equipment and expertise in diagnostics and disease surveillance to support COVID-19 testing in the UK. The Institute is helping in three key areas…

Pirbright confirms African horse sickness outbreak in Thailand

Scientists in the Non-Vesicular Reference Laboratory (NVRL) at The Pirbright Institute have confirmed an outbreak of African horse sickness (AHS) in Thailand. AHS is the most lethal viral disease of horses known and the rapid diagnostic services provided by Pirbright has…

Influenza antibodies made by Pirbright reduce disease in chickens

Scientists at The Pirbright Institute have engineered synthetic antibody molecules that can be administered to poultry to reduce the symptoms of influenza, as well as decreasing the amount of influenza virus they shed into the environment. These results suggest that there is…

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Pervasive differential splicing in Marek’s disease virus can discriminate CVI-988 vaccine strain from RB-1B very virulent strain in chicken embryonic fibroblasts

Marek’s disease is a major scourge challenging poultry health worldwide. It is caused by the highly contagious Marek’s disease virus (MDV), an alphaherpesvirus. Here, we showed that, similar to other members of its Herpesviridae family, MDV also presents a complex landscape…