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Molecular characterization and phylogenetic analysis of Marek’s disease virus in Turkish layer chickens

1. There is no current data about the genotypes of Marek's disease virus (MDV) in Turkish poultry flocks, hence, this study was performed to analyse CVI988/Rispens, turkey herpesvirus (HVT) vaccine viruses and MDV field viruses as well as to perform phylogenetic analysis of…

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Identification and characterization of the vasa gene in the diamondback moth, Plutella xylostella

Vasa is an ATP-dependent RNA helicase, participating in multiple biological processes. It has been widely used as a germ cell marker and its promoter has become a key component of several genetic pest control systems. Here we present the vasa gene structure and its promoter…

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RNAseq reveals of the contribution of interferon stimulated genes to the increased host defense and decreased PPR viral replication in cattle.

Peste des petits ruminants virus (PPRV) is known to replicate in a wide variety of ruminants causing very species-specific clinical symptoms. Small ruminants (goats and sheep) are susceptible to disease while domesticated cattle and buffalo are dead-end hosts and do not…

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Lumpy skin disease is characterized by severe multifocal dermatitis with necrotizing fibrinoid vasculitis following experimental infection

Lumpy skin disease is a high-consequence disease in cattle caused by infection with the poxvirus lumpy skin disease virus (LSDV). The virus is endemic in most countries in Africa and an emerging threat to cattle populations in Europe and Asia. As LSDV spreads into new…

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Complete genome sequence of a lineage IV peste des petits ruminants virus from Turkey, 2018

We report the whole-genome sequence of a peste des petits ruminants virus (PPRV) from a lamb exhibiting clinical signs in Turkey in September 2018. The genome of PPRV/Turkey/Central_Anatolia/2018 shows the highest nucleotide sequence identity (97.63%) to PPRV isolated in…

IBDV infected cell (red), tubulin (green) and the nucleus (blue)

Pirbright scientists show how infectious bursal disease viruses may swap genetic material during infection

Live cell imaging has been used by researchers at The Pirbright Institute to reveal new information about how different strains of infectious bursal disease virus (IBDV) might swap genetic material, a process that could lead to new strains with the potential for causing more…

Herd of cows in the field in Tanzania

Pirbright develops universal foot-and-mouth disease virus test

A diagnostic test that can detect whether an animal has been infected by or vaccinated against any type of foot-and-mouth disease virus (FMDV) has been developed by scientists at The Pirbright Institute and Istituto Zooprofilattico Sperimentale della Lombardia e dell'Emilia…

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Comparison of immunogenicity and protective efficacy of PPR live attenuated vaccines (Nigeria 75/1 and Sungri/96) administered by intranasal and subcutaneous routes

Following the successful eradication of rinderpest, the World Organization of Animal Health (OIE) and the Food and Agriculture Organization (FAO) have set a goal to eradicate peste des petits ruminants (PPR) globally by 2030. Vaccination is being taken forward as the key…

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Characterisation of peste des petits ruminants disease in pastoralist small ruminant flocks in Ngorongoro District of northern Tanzania: variation in clinical syndromes and local diseases names, and bluetongue virus co-infection

Peste des petits ruminants (PPR) disease was first confirmed in Tanzania in 2008 in sheep and goats in Ngorongoro District, northern Tanzania, and is now endemic in this area. This study aimed to characterise PPR disease in pastoralist small ruminant flocks in Ngorongoro…

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Characterisation of peste des petits ruminants disease in pastoralist small ruminant flocks in Ngorongoro District of northern Tanzania: variation in clinical syndromes and local diseases names, and bluetongue virus co-infection

Peste des petits ruminants (PPR) disease was first confirmed in Tanzania in 2008 in sheep and goats in Ngorongoro District, northern Tanzania, and is now endemic in this area. This study aimed to characterise PPR disease in pastoralist small ruminant flocks in Ngorongoro…