Researchers at The Pirbright Institute have used the CRISPR/Cas9 gene editing tool to knock out a gene in Culex quinquefasciatus Say, an understudied species of mosquito that spreads a variety of bird, animal and human diseases, including West Nile virus. The study provides the first characterisation of a gene that determines eye colour in this species, which will prove a valuable marker for researchers looking to modify this mosquito to control wild populations and aid disease prevention.
Researchers from The Pirbright Institute have shown that glutamine, a protein building block, is essential for the replication of Marek’s disease virus in chickens. Their study revealed that cells infected with the virus were unable to survive glutamine deprivation, a finding that could be used to develop treatments for the disease.
Pirbright scientists lead Gnatwork training for international scientists on key vector research skills
Between 4-8 November 2019, the Gnatwork trained a group of 28 international early career researchers at Universidade Federal De Minas Gerais (UFMG), Brazil, to develop the essential skills needed to work with three neglected species of insects that transmit diseases; midges, blackflies and sandflies.