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Prof Bryan Charleston and Dr Linda Dixon who is holding a box of flowers stood in front of a screen with agenda of symposium

Symposium celebrates scientist’s 40-year career

International scientists, colleagues and friends have celebrated the 40-year career of Dr Linda Dixon at a special symposium at The Pirbright Institute. Dr Dixon, who recently retired from leading the African Swine Fever Virus (ASFV) group, is amongst the most highly cited…

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Mapping novel antigenic determinants on foot-and-mouth disease virus serotype Asia 1 using neutralising monoclonal antibody resistant mutants

Foot-and-mouth disease (FMD) is a severe and, highly contagious viral disease caused by FMD virus (FMDV) that primarily targets ungulates. Identifying neutralising antigenic sites on the virus is crucial for understanding the virus's antigenic characteristics. Numerous…

Eight mpox cells under the microscope and coloured bright blue

Mpox

Mpox is a contagious viral disease affecting humans, with global health implications.

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Recombinant infectious bronchitis virus containing mutations in non-structural proteins 10, 14, 15, and 16 and within the macrodomain provides complete protection against homologous challenge

Infectious bronchitis virus (IBV) is the etiological agent of infectious bronchitis, an acute highly contagious economically important disease of chickens. Vaccination uses live attenuated vaccines (LAVs) that are generated via serial passage of a virulent field isolate…

Two brown roosters on grass by a fence

New strategies for infectious bronchitis virus vaccine development

Researchers develop a new method for Infectious bronchitis virus (IBV) vaccine development.

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Qualitative studies on farm managers perception of risk from HPAIV and implementation of biosecurity measures on UK poultry farms

The epidemic of high pathogenicity avian influenza (HPAI) H5N1 in the United Kingdom and Northern Europe from 2021 to 2023 has dwarfed all previous incursions. This fact has driven the need to review biosecurity behaviours and perceptions of virus incursions on commercial…

A single sloth with its hands grasped around a thin branch

Oropouche virus

Oropouche is an emerging virus spread to humans by biting midges and mosquitoes.

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Foot-and-mouth disease vaccine quality: A universal test for intact viral capsids based on detection of VP4

Foot-and-mouth disease virus (FMDV) causes an economically devastating disease of livestock that is controlled in endemic areas by vaccines containing intact inactivated FMDV particles. In this study, a novel monoclonal antibody named 5B6 has been identified and…

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Using minor variant genomes and machine learning to study the genome biology of SARS-CoV-2 over time

In infected individuals, viruses are present as a population consisting of dominant and minor variant genomes. Most databases contain information on the dominant genome sequence. Since the emergence of SARS-CoV-2 in late 2019, variants have been selected that are more…

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Europe needs a sustainably funded influenza research and response network

Influenza viruses have caused four pandemics during the last century.1 The 1918 H1N1 pandemic claimed 20–50 million lives, the 1957 H2N2 pandemic and the 1968 H3N2 pandemic claimed 1–4 million lives each, and the 2009 H1N1 pandemic claimed an estimated 280 000 lives.2,3…