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Research paper

Influence of the lumpy skin disease virus (LSDV) superoxide dismutase homologue on host transcriptional activity, apoptosis and histopathology

Lumpy skin disease virus (LSDV), a Capripoxvirus, is of economic importance in the cattle industry and is controlled by vaccination. A comparison was made of the host response to the two LSDV vaccines Neethling and Herbivac LS, with reference to the well-studied…
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Research paper

Removal of bovine viral diarrhea virus (BVDV) from lumpy skin disease virus (LSDV) vaccine stocks by passage on chorioallantoic membranes of fertilized hens' eggs

Bovine viral diarrhea virus (BVDV) is a common contaminant of Madin-Darby bovine kidney (MDBK) cells as well as fetal calf serum (FCS). It is pathogenic to cattle and regulatory authorities require that veterinary vaccine stocks are free from BVDV. MDBK cells are used in the…
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Research paper

The complete genome sequence of the lumpy skin disease virus vaccine Herbivac LS reveals a mutation in the superoxide dismutase gene homolog

The lumpy skin disease virus (LSDV) vaccine, Herbivac LS, batch 008, was sequenced and found to differ from the Neethling vaccine strain in the locus encoding a superoxide dismutase (SOD) homolog. The presence of a SOD homolog, be it full-length (as in Herbivac LS) or…
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Research paper

The novel capripoxvirus vector lumpy skin disease virus efficiently boosts modified vaccinia Ankara human immunodeficiency virus responses in rhesus macaques

Poxvirus vectors represent promising human immunodeficiency virus (HIV) vaccine candidates and were a component of the only successful HIV vaccine efficacy trial to date. We tested the immunogenicity of a novel recombinant capripoxvirus vector, lumpy skin disease virus (LSDV…
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Research paper

Prevalence and drug resistance in bacteria of the urinary tract infections in Bulawayo province, Zimbabwe

OBJECTIVE: To obtain data on the prevalence of antibiotic resistance in bacteria isolated from patients with suspected urinary tract infection in Bulawayo province, Zimbabwe. METHOD: Over a period of one year, 257 urine samples were analyzed for bacteria by standard…
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Article

£1.6 million awarded to a UK consortium to tackle infectious diseases

Pirbright joins a consortium of six institutes to receive funding of £1.6 million to support collaborative research against infectious diseases. The consortium, which sees world-leading experts from Pirbright, the Liverpool School of Tropical Medicine, UK Health Security…
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Article

African swine fever – what is the current situation?

African swine fever is a highly contagious disease caused by the African swine fever virus. It infects both domestic and wild pigs and has a case fatality rate of up to 100%. There have been outbreaks in Europe in recent years, with the latest near the French border in…
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Article

African swine fever – what is the current situation?

African swine fever is a highly contagious disease caused by the African swine fever virus. It infects both domestic and wild pigs and has a case fatality rate of up to 100%. There have been outbreaks in Europe in recent years, with the latest near the French border in…
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Research paper

Epidemics of Crimean-Congo hemorrhagic fever (CCHF) in Sudan between 2010 and 2020

Crimean-Congo hemorrhagic fever (CCHF) is a zoonotic arboviral disease that poses a great threat to global health in the Old World, and it is endemic in Europe, Asia, and Africa, including Sudan. In this retrospective study, we reviewed previous epidemiological reports about…
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Research paper

The importance of fine-scale predictors of wild boar habitat use in an isolated population

Predicting the likelihood of wildlife presence at potential wildlife-livestock interfaces is challenging. These interfaces are usually relatively small geographical areas where landscapes show large variation over small distances. Models of wildlife distribution based on…
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