Research paper
Immunisation with bacterial expressed VP2 and VP5 of bluetongue virus (BTV) protect ?/? interferon-receptor knock-out (IFNAR?/?) mice from homologous lethal challenge
BTV-4 structural proteins VP2 (as two domains: VP2D1 and VP2D2), VP5 (lacking the first 100 amino acids: VP5?1100) and full-length VP7, expressed in bacteria as soluble glutathione S-transferase (GST) fusion-proteins, were used to immunise Balb/c and ?/? interferon receptor…
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