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Antiserum from mice vaccinated with modified vaccinia Ankara virus expressing African horse sickness virus (AHSV) VP2 provides protection when it is administered 48 h before, or 48 h after challenge

Previous studies show that a recombinant modified vaccinia Ankara (MVA) virus expressing VP2 of AHSV serotype 4 (MVA-VP2) induced virus neutralising antibodies in horses and protected interferon alpha receptor gene knock-out mice (IFNAR ?/?) against challenge. Follow up…

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Vector competence of Culicoides for arboviruses: three major periods of research, their influence on current studies and future directions.

The spectacular and unprecedented outbreaks of bluetongue virus (BTV) that have occurred in Europe since 1998 have led to increased interest in those factors that determine competence of Culicoides biting midges (Diptera: Ceratopogonidae) for arboviruses. In this review the…

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Suppression of a field population of Aedes aegypti in Brazil by sustained release of transgenic male mosquitoes

Dengue is a major mosquito-borne disease, increasing in prevalence and severity; there are no specific drugs or licensed vaccine. It is primarily transmitted by one mosquito species, Aedes aegypti. We released transgenic sterile male mosquitoes in Itaberaba, a suburb of…

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Boosting the FM-index on the GPU: effective techniques to mitigate random memory access

The recent advent of high-throughput sequencing machines producing big amounts of short reads has boosted the interest in efficient string searching techniques. As of today, many mainstream sequence alignment software tools rely on a special data structure, called the FM…

The Pirbright Institute hosts the South Wilts Virus Group Meeting

The South Wilts Virus Group (SWVG) is a forum for virologists in the Wiltshire, Surrey, Berkshire, Oxfordshire region. It was started in 1952 at the Common Cold Unit (CCU) at Harnham Down near Salisbury (hence the name South Wilts Virus Group) as an informal gathering of…

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Co-circulation of H5N6, H3N2, H3N8, and emergence of novel reassortant H3N6 in a local community in Hunan Province in China

Multiple infections of avian influenza viruses (AIVs) in poultry or wild birds contribute to the continued evolution of H5 subtype viruses in nature and provide potential recombination of AIVs of different origins. In this study, we carried out surveillance of AIVs in ducks…

Avian influenza virus

New analysis of the H9N2 strain of bird flu could help prevent veterinary and human pandemics

A new study of a strain of avian influenza virus, which can pose a risk to both poultry and human health, will help guide surveillance efforts and ensure vaccines are more effective; helping prevent serious outbreaks. The H9N2 virus leads to significant losses in poultry…

Influenza research reveals previously unknown factor limiting virus host range

A new study by a group including Dr Munir Iqbal, from The Pirbright Institute, has identified a previously unknown factor which works to limit the host range of influenza viruses. The research, recently published in Nature, has revealed that the avian protein ANP32A works as…

Newcastle disease virus bioimage

Newcastle disease virus

Newcastle disease virus (NDV) causes Newcastle disease, a highly infectious poultry disease.

Newcastle disease virus bioimage

Newcastle disease virus

Newcastle disease virus (NDV) causes Newcastle disease, a highly infectious poultry disease.