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Anaplasma phagocytophilum is an emerging zoonotic pathogen transmitted by Ixodes scapularis that causes human granulocytic anaplasmosis. Here, a high throughput quantitative proteomics approach was used to characterize A. phagocytophilum proteome during rickettsial…

Peste des petits ruminants virus infects a wide range of domestic and wild small ruminants and the host spectrum has recently increased to camels. Despite this host range, the clinical manifestation varies not only between domestic and wild small ruminants but also between…

Pastoral populations around the world hold complex and detailed ethnoveterinary knowledge, essential for the survival of their herds and securing their livelihood. In recent decades, several studies have given attention to local veterinary remedies and practices and their…

Targeting of specific receptors on antigen-presenting cells is an appealing prospect in the production of novel nanoparticulate vaccines. In particular, the targeting of vaccines to dendritic cell (DC) subsets has been shown in models to significantly improve the induction…

BACKGROUND:Ixodid ticks are important vectors of a wide variety of viral, bacterial and protozoan pathogens of medical and veterinary importance. Although several studies have elucidated tick responses to bacteria, little is known about the tick response to viruses. To gain…

Foot-and-mouth disease (FMD) is endemic in Kenya where four serotypes (O, A, SAT 1 and SAT 2) of the virus are currently in circulation. Within 2010 and 2011, the National Laboratory recorded an increase in the number of FMD outbreaks caused by serotype O virus. The…

Vector control using releases of sterile insects is a well-known approach. ‘Genetically sterile’ male Aedes aegypti have been developed and released in a modern realisation of the sterile insect technique. Released engineered males seek out and mate with wild females, with…

Foot-and-mouth disease (FMD) is one of the most highly contagious and economically devastating diseases, that severely constrains the international trade of animals. Vaccination against FMD is a key element in the control of FMD. However, vaccination of susceptible animals…

Integration of human papillomavirus (HPV) viral DNA into the human genome has been postulated as an important etiological event during cervical carcinogenesis. Several recent reports suggested a possible role for such integration-targeted cellular genes (ITGs) in cervical…