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Vaccine being drawn from a vile

Pirbright partners with ECO Animal Health to combat poultry diseases

The Pirbright Institute has entered into a worldwide exclusive partnership with ECO Animal Health Ltd (ECO), a wholly owned subsidiary of ECO Animal Health Group plc, on two new projects to combat significant diseases of poultry. The first project, led by Professor Venugopal…

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Assessment of ante mortem welfare indicators and the pathophysiology of captive-bolt trauma in equids at slaughter

There is limited research into horse slaughter, particularly ante mortem welfare, and the effectiveness of captive-bolt gun (CBG) stunning, despite this being a widely used method worldwide. To address this evidence gap and explore associations between ante and post mortem…

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The global H5N1 influenza panzootic in mammals

Influenza A viruses have caused more documented global pandemics in human history than any other pathogen 1,2. High pathogenicity avian influenza viruses belonging to the H5N1 subtype are a leading pandemic risk. Two decades after H5N1 'bird flu' became established in…

Pirbright launches The Immunological Toolbox website

Scientists from The Pirbright Institute and The Roslin Institute have launched The Immunological Toolbox, a website that provides a platform for veterinary researchers to find resources and collaborate. The Toolbox aims to remove barriers to veterinary vaccine development by…

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Expanding the transgene expression toolbox of the malaria vector Anopheles stephensi

Anopheles stephensi Liston, 1901 (Diptera: culicidae) is a competent vector of Plasmodium falciparum (Haemosporida: plasmodiidae) malaria, and its expansion in the African continent is of concern due to its viability in urban settings and resistance to insecticides. To…

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Serological Cross-reactivity between Crimean-Congo Haemorrhagic Fever Virus (CCHFV) and Nairobi Sheep Disease Virus (NSDV) glycoprotein C (Gc)

Cross-reactivity to viruses of the Orthonairovirus genus can potentially interfere with serological assays when employed for serosurveillance in regions where two or more genus members overlap in their distribution. To investigate this, Crimean-Congo haemorrhagic fever virus…

Mosquito taking a blood meal on human skin

Pirbright scientists create mosquito GM method using scorpion venom component

Researchers at The Pirbright Institute have successfully inserted a scorpion venom gene into mosquitoes, which causes their paralysis after they feed on blood. This particular venom component is specific for arthropods, such as insects and millipedes, and harmless to mammals…

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An evaluation of financial losses due to lumpy skin disease outbreaks in dairy farms of Northern Thailand

Lumpy skin disease (LSD) poses a significant threat to the cattle industry, resulting in adverse economic consequences in affected countries. This study aims to estimate the financial losses economic impact due to LSD outbreaks in dairy farms in northern Thailand. Based on a…

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GGCX promotes Eurasian avian-like H1N1 swine influenza virus adaption to interspecies receptor binding

The Eurasian avian-like (EA) H1N1 swine influenza virus (SIV) possesses the capacity to instigate the next influenza pandemic, owing to its heightened affinity for the human-type α-2,6 sialic acid (SA) receptor. Nevertheless, the molecular mechanisms underlying the switch in…

UK-China Centre of excellence for research on avian diseases group photo

UK-China avian disease conference will help enhance food security, says Pirbright scientist

Researchers from The Pirbright Institute and several Chinese institutes gathered in Zhengzhou, China between 23 and 25 September 2019 to attend the annual UK-China Centre of Excellence for Research on Avian Diseases (CERAD) conference. The event also included an opening…