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Culicoides-borne Orbivirus epidemiology in a changing climate

Orbiviruses are of significant importance to the health of wildlife and domestic animals worldwide; the major orbiviruses transmitted by multiple biting midge (Culicoides) species include bluetongue virus, epizootic hemorrhagic disease virus, and African horse sickness virus…

A group of chickens gather around a watering hole

Ancient DNA shows how a chicken virus evolved to become more deadly

Experts from The Pirbright Institute have worked with an international team of scientists led by Oxford and LMU Munich to trace the evolution of Marek's disease virus (MDV). The highly contagious poultry pathogen causes fatal disease in chickens worldwide, costing the…

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Chicken caecal enterotypes in indigenous Kadaknath and commercial Cobb chicken lines are associated with Campylobacter abundance and influenced by farming practices

Identifying farming practices that decrease susceptibility to infectious diseases and optimise food conversion efficiency is valuable for chicken welfare and productivity, the environment, and public health. Enterotypes can be used to define microbial community phenotypes…

Six people stood around a plaque in front of a screen with a red backgroun containing text that reads Pirbright Institute and Chinese text. Pirbright's Venu Nair and Yongxiu Yao stood in the middle to the right of the plaque.

Avian disease research: Pirbright scientists strengthen UK-China collaboration

A team of avian disease researchers from The Pirbright Institute have visited China to strengthen international ties. The poultry industry is a significant partner in the quest for global food security and provides a significant source of protein for billions of people…

cow being vaccinated at the Compton site, Pirbright Institute

Pirbright shares in global vaccines fund

The Pirbright Institute is to share in a £6.3m fund for five Global Vaccines Networks. The investment will allow Pirbright, in partnership with The Roslin Institute at the University of Edinburgh, to further develop the International Veterinary Vaccinology Network (IVVN)…

culicoides biting midge sitting on a green stalk pirbright

Pirbright joins hub to tackle vector-borne diseases

The Pirbright Institute is to work with scientific partners to establish a centre where experts tackle diseases spread by insects, ticks and mites. The £1.5m One Health Vector-Borne Diseases Hub is led by Imperial College London and funded by Defra and the Biotechnology and…

culicoides biting midge sitting on a green stalk pirbright

Pirbright joins hub to tackle vector-borne diseases

The Pirbright Institute is to work with scientific partners to establish a centre where experts tackle diseases spread by insects, ticks and mites. The £1.5m One Health Vector-Borne Diseases Hub is led by Imperial College London and funded by Defra and the Biotechnology and…

African domestic cows in Tanzania

Foot-and-mouth disease control: Nagoya protocol poses ‘significant challenges’

An international agreement designed to share the benefits of genetic resources is presenting ‘significant logistical challenges’ to the control of transboundary livestock diseases, according to specialist researchers. The 2010 Nagoya Protocol on Access and Benefit Sharing…

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Distinct effector functions mediated by Fc regions of bovine IgG subclasses and their interaction with Fc gamma receptors

Cattle possess three IgG subclasses. However, the key immune functions, including complement and NK cell activation, and enhancement of phagocytosis, are not fully described for bovine IgG1, 2 and 3. We produced chimeric monoclonal antibodies (mAbs) consisting of a defined…

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Distinct effector functions mediated by Fc regions of bovine IgG subclasses and their interaction with Fc gamma receptors

Cattle possess three IgG subclasses. However, the key immune functions, including complement and NK cell activation, and enhancement of phagocytosis, are not fully described for bovine IgG1, 2 and 3. We produced chimeric monoclonal antibodies (mAbs) consisting of a defined…